Centre National De La Recherche Scientifique

Institut National De La Sante Et De La Recherche Medicale

Université Grenoble Alpes

Imv Technologies

Swissgenetics

Centre National De La Recherche Scientifique-cnrs

Institut National De La Sante Et De La Recherche Medicale (inserm)

Jessica Escoffier

Eric Schmitt

Christophe Arnoult

Guillaume Martinez

The invention relates to a method for increasing the lifespan of animal sperm comprising contacting said sperm with an inhibitor of Slo3 potassium channel. The invention also relates to a use of an inhibitor of Slo3 potassium channel, for increasing the lifespan of animal sperm or motility of capacitated animal sperm, comprising contacting an inhibitor of Slo3 potassium channel with said sperm. Moreover, the invention relates to an artificial insemination instrument for use in artificial insemination of an animal, comprising animal sperm in contact with an inhibitor of Slo3 potassium channel. The invention also relates to a method for artificially inseminating an animal using said artificial insemination instrument. Eventually, the invention relates to a method for increasing the fertility of an animal, comprising contacting sperm of said animal with an inhibitor of Slo3 potassium channel; then artificially inseminating said animal with said sperm.

Method for increasing the lifespan and motility of animal sperm using an inhibitor of Slo3 potassium channel

Growing community of inventors

Saint Etienne de Crossey, France

Jessica Escoffier