Ventana Medical Systems, Inc.

Jessica A Wifall

Brian Howard Kram

Kevin David Marshall

Michael Otter

Henning Groll

Austin Micheil Ashby

Simon Jonathon Spence

Matthew Ketterer

Christine Tse

Benjamin James

Josh Harrison

Kevin Talucci

Carl David Martin

Lisa A Jones

Yu-Heng Cheng

Mirek Holubec

Patrick Brown

Sacha Dopheide

Andrew Watkins

Bryan Barnes

Lizhen Pang

A real-time imaging method and system for monitoring an assay process performed on a biological sample is described. In some embodiments, the method and system can be used to measure and control a reagent volume confined to a space between a cover and a substrate, which is particularly useful for controlling for evaporation in a thin-film staining environment. In particular embodiments, the disclosed reagent volume sensing and replenishment method and system are resistant to system noises generated during operation, for example, system noise due to vibration, field of view blockage by dispenser systems, differences in reagent colors, and changing tissue colors.

System and method for real-time volume control

A specimen processing system is capable of processing specimens carried on slides. The specimen processing system can sequentially deliver slides and opposables to specimen processing stations. The specimen processing stations can use the opposables to apply a series of liquids to the specimens. The applied liquid can be moved along the slide using capillary action while the specimen processing stations control the processing temperatures. The applied liquid can be in a fluid-carrying gap. The opposable can contact the slide to vary a cross section of the fluid-carrying gap.

Opposables and automated specimen processing systems with opposables

A specimen processing system is capable of processing specimens carried on slides. The specimen processing system can sequentially deliver slides and opposables to specimen processing stations. The specimen processing stations can use the opposables to apply a series of liquids to the specimens. The applied liquid can be moved along the slide using capillary action while the specimen processing stations control the processing temperatures.

Specimen processing systems and methods for aligning slides

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Oro Valley, AZ, United States of America

Jessica A Wifall