Epix Therapeutics, Inc.

Miramar Labs, Inc.

Miradry, Inc.

Foundry Innovation & Research 1, Ltd.

Advanced Cardiac Therapeutics, Inc.

Creo Medical Limited

Atcor Medical Pty Limited

Jessi E Johnson

Christopher Loew

Steven W Kim

Daniel Elliott Francis

Dorin Panescu

Josef Vincent Koblish

Ted Y Su

Alexey Salamini

Mark E Deem

Yoav Ben-Haim

Donghoon Chun

Eric Andrew Schultheis

Peter Smith

Hanson S Gifford, Iii

Douglas S Sutton

Fiachra M Sweeney

Peter J Bentley

Kevin Shan

Conor M Hanley

Daniel K Hallock

Friedrich Wetterling

Stephen Sheridan

Dong Hoon Chun

Pablo Martin

Shailendhar Saraf

Shriram Raghunathan

Dan Hallock

Dan Francis

John F McCarthy

Christopher Paul Hancock

George Christian Ullrich

Louis Turner

David Edward Webb

Sunmi Chew

Leo Kopelow

Sean Quinlan

Simon Meadowcroft

Oliver Hao-Yuan Shay

Axel Brisken

Miriam Taimisto

Lillian Lei Dai

Hanson S Gifford Iii

Radiometric systems may comprise a radiometer, an antenna and a processor communicatively coupled together. The processor may provide a contact-focused output based on filtering or other processing of a raw radiometric output signal. The contact-focused output may facilitate determination of whether contact has been achieved and/or assessment of contact. A miniaturized reflectometer may be configured to determine an amount of reflected power from the antenna. The processor may be configured to determine a reflection coefficient of the reflected power determined by the reflectometer and to identify tissue type based on the reflection coefficient. Systems and methods for facilitating deeper temperature measurements of a radiometer are described.

Radiometric tissue contact and tissue type detection

Wireless, variable inductance and resonant circuit-based vascular monitoring devices, systems, methodologies, and techniques, including specifically configured anchoring structures for same, are disclosed that can be used to assist healthcare professionals in predicting, preventing, and diagnosing various heart-related and other health conditions.

Wireless resonant circuit and variable inductance vascular monitoring implants and anchoring structures therefore

Methods, apparatuses and systems are provided for non-invasive delivery of microwave therapy. Microwave energy may be applied to epidermal, dermal and subdermal tissue of a patient to achieve various therapeutic and/or aesthetic results. In one embodiment, the microwave energy is applied to a target tissue via an energy delivery applicator connected to an energy generator. The energy delivery applicator may comprise one or more antennas, including monopole, dipole, slot and/or waveguide antennas (among others) that are used to direct the microwave energy to the target tissue. The energy delivery applicator may also comprise a cooling element for avoiding thermal destruction to non-target tissue and/or a suction device to localize thermal treatment at specific portions of a skin fold.

Methods, devices, and systems for non-invasive delivery of microwave therapy

Systems, devices and methods of determining orientation of a distal end of a medical instrument (e.g., electrode-tissue orientation of an RF ablation catheter) are described herein. One or more processors may be configured to receive temperature measurements from each of a plurality of temperature-measurement devices distributed along a length of the distal end of the medical instrument and determine the orientation from a group of two or more possible orientation options based on whether temperature measurement values or characteristics of temperature response determined from the temperature measurement values satisfy one or more orientation criteria.

Methods of determining catheter orientation

An electrosurgical apparatus comprising an electrosurgical forceps instrument that combines la robust jaw opening mechanism with an a microwave energy delivery mechanism. The instrument includes a rigid bracket mounted at a distal end of a flexible shaft, wherein a pair of jaws are pivotably mounted on the rigid bracket. The instrument includes an energy delivery structure comprising a flexible dielectric substrate having a first electrode and an second electrode formed on one of the pair of jaws, wherein the first electrode and the second electrode are arranged to emit microwave energy. The electrosurgical apparatus may also comprise a handpiece that combines rotation control of an electrosurgical instrument with both power delivery and end effector actuation (e.g. jaw closure, blade retraction or the like).

Electrosurgical apparatus

An implantable ultrasonic vascular sensor for implantation at a fixed location within a vessel, comprising at least one ultrasound transducer, a transducer drive circuit, and means for wirelessly transmitting ultrasound data from the at least one ultrasound transducer.

Implantable ultrasonic vascular sensor

As shown in FIG.and FIG., the health monitoring systemof one embodiment includes an electromagnetic transmitterconfigured to transmit an electromagnetic signal towards a target body region on a user; an electromagnetic receiverconfigured to receive reflected energy from a target body region on a user; a calibration sensorthat measures reference cardiovascular-related parameters of a user (such as vessel pressure, stiffness, or motion); and an activity sensorconfigured to detect the activity state of a user. The system also includes an attachment mechanismfor fixing the electromagnetic transmitter, electromagnetic receiver, calibration sensor and activity sensor to the user; and a stand-off mechanismfor fixing the electromagnetic transmitter and electromagnetic receiver at a known standoff distance from a target body region on the user.

System and method for cardiovascular health monitoring

Systems and methods for facilitating assessment of a nature of contact between an electrode assembly of an ablation catheter and viable body tissue are disclosed herein. In some embodiments, a method comprises obtaining a first detected voltage between a first electrode and a second electrode, wherein the first and second electrodes are positioned along an electrode assembly of the ablation catheter, and wherein the first electrode is distal to the second electrode, obtaining a second detected voltage between the second electrode and a third electrode, the third electrode positioned proximal to the second electrode.

Contact assessment between an ablation catheter and tissue

According to some embodiments, a medical instrument comprises an elongate body having a proximal end and a distal end and a pair of electrodes or electrode portions (for example, a split-tip electrode assembly). Systems and methods are described herein that perform contact sensing and/or ablation confirmation based on electrical measurements obtained while energy of different frequencies are applied to the pair of electrodes or electrode portions. The contact sensing systems and methods may calibrate network parameter measurements to compensate for a hardware unit in a network parameter measurement circuit or to account for differences in cables, instrumentation or hardware used.

Contact sensing systems and methods

Systems for determining catheter orientation

Growing community of inventors

Santa Clara, CA, United States of America

Jessi E Johnson