Clearside Biomedical, Inc.

Copernicus Therapeutics, Inc.

Jesse Yoo

Rafael Victor Andino

Vladimir Zarnitsyn

Christopher John Brooks

David J Trettin

Trent Kahute

Justin William Arsenault

Stephanie Lewis

Mark J Cooper

Andrew Bauer

Samirkumar Rajnikant Patel

Trent John Kahute

Daniel White

Shelley Eckert Hancock

Glenn Noronha

Thomas Edward Godfrey

Keleigh Jo Strudthoff

Keleigh Jo Mahn

Samirkumar Patel

Stephanie Elaine Lewis

David Jackson Trettin

Andrew Kent Bauer

Rick Mcelheny

Robert C Moen

Donna Taraborelli

An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location.

Apparatus and methods for ocular injection

Devices, methods, and kits for ocular drug delivery are described herein. An apparatus can include a housing, an energy storage member, a barrel, and a hub. The housing contains the energy storage member. A proximal end portion of the barrel is coupled to a distal end portion of the housing. The barrel is configured to contain medicament and includes at least a portion of a piston and an elastomeric member. The piston is configured to move the elastomeric member within the barrel in response to a force produced by the energy storage member. The hub is coupled to a distal end portion of the barrel. An inner surface of the hub defines a nozzle through which the medicament flows when the elastomeric member moves within the barrel. The nozzle and the energy storage member are collectively configured to produce a fluid jet to access a target location within an eye.

Systems and methods for ocular drug delivery

Growing community of inventors

Snellville, GA, United States of America

Jesse Yoo