R.p.scherer Technologies, Inc.

Redwood Bioscience, Inc.

Amgen Inc.

Jesse M McFarland

David Rabuka

Romas Alvydas Kudirka

Albert W Garofalo

Aaron Edward Albers

Robyn M Barfield

Penelope M Drake

Gregory W deHart

Stepan Chuprakov

Albert W Garafalo

Ryan D White

Russell Graceffa

Daniel A Erlanson

Xiao Mei Zheng

John R Butler

Yongwei Wu

Abhisek Banerjee

Joon Won Jeong

Jeffrey Iwig

Shuyan Yi

The present disclosure provides conjugate structures and hydrazinyl-pyrrolo compound structures used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.

Hydrazinyl-pyrrolo compounds and methods for producing a conjugate

The present disclosure provides anti-CD22 antibody-maytansine conjugate structures. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.

Anti-CD22 antibody-maytansine conjugates and methods of use thereof

The present disclosure provides anti-HER2 antibody-maytansine conjugate structures. The disclosure also encompasses methods of production of such conjugates, as well as methods of using the same.

Anti-HER2 antibody-maytansine conjugates and methods of use thereof

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for manufacturing compounds of the invention and therapeutic uses thereof. 

N-cyano-7-azanorbornane derivatives and uses thereof

The present disclosure provides conjugate structures and hydrazinyl-substituted heteroaryl compounds used to produce these conjugates. The disclosure also encompasses methods of production of such conjugates and compounds, as well as methods of using the same.

Hydrazinyl-substituted heteroaryl compounds and methods for producing a conjugate

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Berkeley, CA, United States of America

Jesse M McFarland