Mystic Pharmaceuticals, Inc.

Jesse Hancock

Timothy R Sullivan

Michael W Shaw

Jeffrey Gjertsen

Jeff Gjertsen

Phillip Goodman

Timothy Sullivan

The multi-chambered well dosage form and device disclosed herein can be single or multi dose capable for administration of pharmaceuticals of a range of particle sizes. The present dosage devices and systems provide for improved efficiency and patient ease of use owing to its compact size and simple design, low cost, and consistent, contamination free dosing of dry powder medicaments or other agents. The present disclosure provides a multi-chambered dosage form containing dry powder medical composition containing chamber well with an internal piercing device and one or more adjacent gas-filled chamber wells to aid the dispense of the powder contents to the user and in certain embodiments, without the requirement of an external energy sources common with active devices known in the art. Said methods, systems and devices provide increased ejection fraction and hence greater efficiency of drug delivery above that as provided by current devices.

Devices and systems for air assisted dry powder administration

A piercing device for use in internally pierced blister delivery devices include a base, a piercer body and an internal fluid path. The internal fluid path includes one or more inlet channels into a central cavity which is connected to one or more delivery channels and exit ports. The cavity is defined by angular walls and top to create turbulence in the fluid flow and to produce a controllable spray, mist, drops, plume or stream delivery. The piercer body also provides a pointed lancet disposed in the center of the exit ports for piercing the lidstock of a formed blister.

Controllable rate turbulating nozzle

The present invention discloses a system for applying antigens or other diagnostic substances to the skin of a subject for allergy testing. The system is comprised of fully contained predetermined quantities of antigenic or other testing material contained in sealed unit doses that maintain sterility and provide for precise handling and administration. Each unit dose contains an internal mechanism. The mechanism provides for piercing the laminate and comprises an internal channel for fluid communication, and may have an abrasive protrusions at the tip for piercing or abrading the skin surface to aid in generating a diagnostic response. The unit dose or doses may be housed in devices that provide for administration of the test material to the subject wherein the applicator section may contain protrusions for piercing or abrading the skin of a subject.

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Cedar Park, TX, United States of America

Jesse Hancock