Visx, Inc.

Coherent, Inc.

Jerzy Orkiszewski

Jan C Wysopal

Carl F Knopp

William D Fountain

H Alfred Sklar

Michael Persiantsev

Hanna J Hoffman

David A Dewey

David Trost

Michael Arnett

Robert J Rorden

Gregory Dumond

A method and system is described that greatly improves the safety and efficacy of ophthalmic laser surgery. The method and system are applicable to precise operations on a target subject to movement during the procedure. The system may comprise the following elements: (1) a user interface, (2) an imaging system, which may include a surgical microscope, (3) an automated tracking system that can follow the movements of an eye, (4) a laser, (5) a diagnostic system, and (6) a fast reliable safety means, for automatically interrupting the laser firing.

Automated laser workstation for high precision surgical and industrial interventions

A method, apparatus and system for template-controlled, precision laser interventions is described that greatly improves interventions such as laser microsurgery, particularly ophthalmic surgery, and industrial micromachining. The instrument and system are applicable to those specialties wherein the positioning accuracy of laser lesions is critical, such as whenever precise operations on a target or series of targets subject to movement during the procedure are to be effected. The system includes a user interface, wherein the user can either draw, adjust, or designate particular template patterns overlaid on a live video images of the target (such as the cornea) which are stabilized and produce an apparently stationary display of the target and provide the means for converting the template pattern into a sequence of automatic motion instructions to direct a laser beam to be sequentially applied replicating the designated template pattern into the corresponding surgical or industrial site.

A method, apparatus and system for a transverse tracker is described that can greatly improve the accuracy, speed, range, reliability, versatility, safety, and efficacy of interventions such as laser microsurgery, particularly ophthalmic surgery, and industrial micromachining. The instrument and system disclosed are applicable to those situations wherein the positioning accuracy of laser lesions is critical, and/or whenever precise operations on a target or series of targets subject to random movement during a procedure are to be effected. The present invention provides means for stabilizing the motion of targets in a plane perpendicular to the axial direction, thus allowing an imaging system, diagnostics illumination, and/or laser beam to maintain a lock on the target area, regardless of its movement. The invention also provides means for recording eye movements in real time and in which data can be stored and manipulated for the purpose of compensating for lateral target motion by either hardware or software means. Unique attributes provided in the tracking system include means for (1) sensing contrast in recognizable large scale boundaries such as the change between the cornea/sclera interface (limbus), thereby to determine the absolute location and orientation of these boundaries, all without having to resort to digital sampling techniques and (2) dual mode operation of an electronic control system compatible with all analog technologies, thereby substantially increasing the speed of operations over other, comparable digital method. The tracking system of the invention is at least comprised of illumination sources, imaging optics, a sensor such as a position-sensitive detector, a movable optical element such as a mirror, a two-dimensional logic board, and a dedicated microprocessor, including appropriate signal processing firmware and software. Additional optics can be incorporated to provide interface with other assemblies such as depth tracking, target viewing and/or laser surgery subsystems. The system of the invention affords considerable flexibility in selecting particular components such as the illuminators, detectors and servo devices, which, in turn, allows broad application of this system to tracking tasks in diverse medical surgical, diagnostic, and industrial settings.

System for detecting, measuring and compensating for lateral movements of a target

Typically, a laser emits significant energy after a control signal is generated to disable the power supply. The inherent delay between generation of a control signal for shutting off a laser power supply and actual termination of an output beam pulse in response to the control signal, is compensated in the context that the control signal is generated automatically upon coincidence of measured output beam power with a preset threshold value. Power supplied to a laser is modulated to cause generation of a pulsed laser output beam. The cumulative energy of each output beam pulse is monitored and a feedback signal indicative of measured output beam pulse energy is supplied to the power supply. The feedback signal is compared with a user-selected threshold value, and a control signal is generated for terminating the output beam pulse (by terminating input power to the laser) when the measured output pulse energy reaches the threshold value. By generating the threshold signal to have a value representing a threshold output beam pulse energy that is lower than a desired output beam pulse energy, the threshold signal is generated in a manner which compensates for the inherent delay between generation of the control signal and the actual termination of the output beam pulse in response to the control signal. This prevents delivery of significant output beam energy in excess of a user-selected amount.

Electronically pulsed laser system

A method, apparatus and system for template-controlled, precision laser interventions is described that greatly improves the accuracy, speed, range, reliability, versatility, safety, and efficacy of interventions such as laser microsurgery, particularly ophthalmic surgery, and industrial micromachining. The instrument and system are applicable to those specialties wherein the positioning accuracy of laser lesions is critical, wherever accurate containment of the spatial extent of a laser lesion is desirable, and/or whenever precise operations on a target or series of targets subject to movement during the procedure are to be effected. The system thus comprises the following key elements: (1) a user interface, consisting of a video display, microprocessor and controls, (2) an imaging system, which may include a surgical video microscope with zoom capability, (3) an automated 3D target acquisition and tracking system that can follow the movements of the subject tissue, for example an eye, during the operation, thus allowing the surgeon/user to predetermine his firing patern based on an image which is automatically stabilized over time, (4) a laser, with which can be focused so that only the precise lesions described by the user interface are effected, (5) a diagnostic system, incorporating a mapping and topography means for measuring precise surface shapes prior to and subsequent to a procedure, said measurements to be executed on-line within time scales not limited to human response times, and (6) a fast reliable safety means, whereby the laser firing is interrupted automatically, should any conditions arise to warrant such interruption of the procedure.

Automated laser workstation for high precision surgical and industrial

A method, apparatus and system for a transverse tracker is described that can greatly improve the accuracy, speed, range, reliability, versatility, safety, and efficacy of interventions such as laser microsurgery. The present invention provides means for stabilizing the motion of targets in a plane perpendicular to the axial direction, thus allowing an imaging system, diagnostics illumination, and/or laser beam to maintain a lock on the target area, regardless of its movement. Unique attributes provided in the tracking system include means for (1) sensing contrast in recognizable large scale boundaries such as the change between the cornea/sclera interface (limbus), thereby to determine the absolute location and orientation of these boundaries, all without having to resort to digital sampling techniques and (2) dual mode operation of an electronic control system compatible with all analog technologies, thereby substantially increasing the speed of operations over other, comparable digital method. The tracking system of the invention is at least comprised of illumination sources, imaging optics, a sensor, a movable optical element, a two-dimensional logic board, and a dedicated microprocessor, including appropriate signal processing firmware and software. Additional optics can provide interface with depth tracking, target viewing and/or laser surgery subsystems. The invention affords considerable flexibility in selecting illuminators, detectors and servo devices, which, allows broad application of this system to diverse medical surgical, diagnostic, and industrial settings.

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Livermore, CA, United States of America

Jerzy Orkiszewski