Merck Patent Gmbh

Merck Patent Gesellschaft MIT Beschrankter Haftung

Merck Patent Gesellschaft

Merck Patent Gesellschaft MIT Beschr&auml;nkter Haftung

Jerzy Meduski

Herwig Buchholz

Thomas Rudolph

Angela Dudda

The invention relates to the use of at least one flavonoid having an uncharged flavan skeleton as synergist for enhancing the action of self-tanning substances, such as trioses and tetroses, in cosmetic and dermatological formulations and to corresponding novel compositions and to the preparation thereof.

Flavonoids as synergists for enhancing the action of self-tanning substances

The present invention relates to novel compositions containing ascorbic acid with an increased bioavailability of this vitamin. These compositions are useful as food supplements possessing preventive properties against damages of human organs, including skin, tissues and cells due to oxidative stress or damages.

Ascorbate-isoquercetin compositions

The present invention relates to novel compositions containing a combination of the plant St. John's Wort (L.), its extracts of active ingredients and derivatives of dihydro- and tetrahydrofolic acid. This natural formulation is useful for the treatment and prevention of depression with a better effect than the ingredient compounds alone.

Natural formulation for the treatment and prevention of depression, containing St. John's Wort and derivatives of dihydro- and tetrahydrofolic acid

Compositions and pharmaceutical compositions are described which comprise: a component A comprising one or more flavonol glycosides, a component B comprising one or more tetrahydrofolic acid compounds, a component C comprising one or more calcium supplements, and a component D comprising one or more magnesium supplements. Methods of using such compositions and pharmaceutical compositions to treat and/or prevent osteoporosis and/or an inflammatory joint disease are also described.

Compositions for the treatment of inflammatory joint diseases and osteoporosis

The present invention relates to novel compositions containing a mixture of two or three bioflavonols like isoquercetin, quercetin-4&prime;-glycoside, rutin and quercetin, which show differences in their pharmacokinetics. These compositions are useful as food supplements possessing preventive properties against damage to human tissues due to their antioxidant properties. Furthermore, these compositions secure a continuum of the presence of bioflavonols having the same aglycone in human plasma over an extended period of time.

Compositions comprising a mixture of bioflavonols

This invention relates to a composition containing the three active ingredients: a) one or more phosphatidyl serines, b) one or more methyl transporters, and c) one or more compounds selected from methyl and methylene donors.

Compositions for the treatment and prevention of neurological and pathopsychological diseases

The present invention relates to novel, orally administered compositions comprising two redox systems: reduced ascorbic acid in a sustained release form and oxidized isoquercetin with an increased concentration of reduced vitamin C over a prolonged time in the brain. These compositions are useful as neuroprotective agents possessing preventive properties against memory dysfunctions.

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Playa Del Rey, CA, United States of America

Jerzy Meduski