Iowa State University Research Foundation Inc

Jerry W Young

Donald C Beitz

Ling Li

Arnold R Hippen

Shangara S Dehal

Kimberly K Buhman

The use of glucagon as a metabolic conditioner for dairy cows and other ruminants is described. The glucagon is preferably administered in an amount of from 1-10 mg per day, preferably during the time period beginning 7 days before calving and continuing until 21 days after calving. The administration of glucagon decreases the incidence of metabolic diseases and metabolic imbalances associated with fatty liver, allows cows to reach peak mile production sooner, and results in increased feed intake during the early stages of lactation.

Use of glucagon as a metabolic conditioner for dairy cows and other

A method of decreasing plasma cholesterol is disclosed. The method includes oral administration of coprostanol-producing bacteria to humans. These organisms, once in the small intestine, will reduce free cholesterol to coprostanol, which is absorbed poorly. Pharmaceutical compositions for delivery are included as are different methods of delivery such as placing the microorganisms in food.

Oral administration of coprostanol producing microorganisms to humans to

Cholesterol reductase was discovered in certain green plant parts. The enzyme is known to be present in several bacteria that commonly inhabit the digestive tract of animals. Eubacteria species A.T.C.C. 21408 is one such cholesterol reductase-containing bacterium. It is concentrated from a homogenate, preferably of leaves of plants or from bacteria or other organisms to provide a cell-free, cholesterol reductase-enriched preparation that can be used to decrease cholesterol content of food substances.

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Ames, IA, United States of America

Jerry W Young