Zoetis Services LLC

Pfizer Corporation

Pharmacia & Upjohn Company

Zoetis LLC

Jerry W Bowman

Andrea Joy Gonzales

Mark J Mitton-Fry

Donald Wayne Mann

Matthew Joseph Birchmeier

Pamela J Berlinski

Steven Glenn Kamerling

Timothy G Geary

Alan R Friedman

Described herein is pyrrolo{2,3-d}pyrimidine compounds, their use as Janus Kinase (JAK) inhibitors, pharmaceutical compositions containing this compounds, and methods for the preparation of these compounds.

Pyrrolo[2,3-D]pyrimidine compounds

Pyrrolo[2,3-d]pyrimidine compounds

Described herein is pyrrolo{2,3-}pyrimidine compounds, their use as Janus Kinase (JAK) inhibitors, pharmaceutical compositions containing this compounds, and methods for the preparation of these compounds.

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The present invention provides a novel radioactive neuropeptide represented by the formula Lys-His-Glu-Tyr.sup.--I -Leu-Arg-Phe-amide. The invention also provides a method for detecting anthelmintic activity of a compound using the novel neuropeptide of the present invention in a receptor binding assay. The novel radioactive neuropeptide has potent bioactivity in Ascaris suum neuromuscular strips, and therefore is particularly useful for high volume screening for potential anthelmintic compounds.

Method for discovering novel anthelmintic compounds

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Lawton, MI, United States of America

Jerry W Bowman