Other

The United States of America, as Represented by the Secretary, Department of Health and Human Services

New York University

Jerry Lee Keith

John B Robbins

Rachel Schneerson

Joanna Kubler-Kielb

Zuzana Biesova

Louis H Miller

Ruth S Nussenzweig

Fathy Majadly

Darrell T Liu

Christopher P Mocca

Tod J Merkel

Xiaoming Yang

A clip configured to releasably secure opposing halves of a fiberglass shroud surroundably mounted to a cellular tower. The clip includes a first tube member and a second tube member wherein the second tube member has a diameter that is less than that of the first tube member. The second tube member is slidably coupled with the first tube member wherein the second tube member is partially disposed within the interior volume of the first tuber member. A first post and a second post are distally mounted and each have a portion extending into the first tube member and second tube member respectively. A spring is present within the interior volume of the first tube member and second tube member and is operably coupled to the first post and second post. The first post and second post have angular portions configured to help maintenance of the clip's position.

Clip

Disclosed are immunogenic conjugates which elicit an immune response toproteins. In particular examples, theproteins include sexual stage surface proteins, circumsporozoite protein (CSP), or immunogenic portions of CSP. Also provided herein are immunogenic compositions including one or more of the disclosed immunogenic conjugates and a pharmaceutically acceptable carrier. Further provided is a method of eliciting an immune response toin a subject, comprising administering to the subject an immunogenic composition disclosed herein.

Multicomponent vaccine for malaria providing long-lasting immune responses against plasmodia

Disclosed are immunogenic conjugates having the general formula:M2e-Cys-S&#x2014;CH&#x2014;C(O)&#x2014;NH&#x2014;CH&#x2014;CH2-C(O&#x2014;)NH-Lys-Pr,were M2e is the influenza M2 ectodomain (M2e) peptide; Cys is a cysteine amino acid residue present in the M2e peptide; S the sulfur present in the cysteine amino acid residue; CH2-CO&#x2014;NH&#x2014;CH2-CH2-CO the linking group; NH the amine group present in a lysine residue of the carrier; Lys is a lysine amino acid residue and Pr the carrier protein. Also disclosed are isolated immunogens that include an immunogenic fragment of an influenza HA protein including the polybasic cleavage site, wherein the immunogenic fragment of the influenza HA protein has been modified to remove an N-terminal leader amino acid sequence and a C-terminal transmembrane domain. Also disclosed are methods producing an influenza vaccine specific for an identified influenza strain.

Vaccines against influenza virus

A support or jack that hangs from the tabs of a poured concrete wall. The support may include a hook that engages in an opening in the tab, to connect the support to the wall. The support may include a slot in which the tab is received, to connect the support to the wall.

Bracket and method for supporting a platform from concrete form tabs

The present invention provides a vaccine production strain ofthat produces a pertussis toxin in high yield. The present invention provides a method for creating acell line which produces atoxin comprising the steps of introducing a plasmid containing a DNA encoding antibiotic resistance into astrain, selecting for isolates in which the DNA encoding antibiotic resistance is recombinantly incorporated into the chromosome in place of thetoxin gene, introducing a plasmid containing DNA encoding subunits of thetoxins into theisolates; and, selecting for isolates in which DNA encodingtoxin subunit is recombinantly incorporated into the chromosome, the resulting cells producing thetoxin. The present invention further provides a method for creating acell line which produces atoxin and does not express filamentous hemagglutinin.

High yield pertussis vaccine production strain and method for making same

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Senecaville, OH, United States of America

Jerry Lee Keith