Csl Limited

Stb, Ltd.

Jerry Kanellos

Martin James MacPhee

Dawson Beall

Teresa Martinelli

Belinda Wilmer

Michael John Kleinig

Malgorzata Kupczyk

Adrian Malcolm Oates

Grace Demaria

Neil Goss

Disclosed are solid and frozen haemostatic materials and dressings consisting essentially of a fibrinogen component and a fibrinogen activator. Also disclosed are methods of treating internal wounded tissue in a mammal by applying one or more of these haemostatic materials and dressings.

Methods and dressings for sealing internal injuries

The present invention relates to methods for purifying fibrinogen. In one aspect, the present invention relates to a method of separating fibrinogen from plasma fraction I precipitate. In another aspect, the invention relates to the purification of fibrinogen using ion exchange chromatography.

Separation of fibrinogen from plasma proteases

Method of obtaining a fibrinogen enriched preparation by (i) adding an effective amount of a sulphated polysaccharide (SPS) to a fibrinogen containing solution to form a fibrinogen containing precipitate and (ii) extracting fibrinogen from the fibrinogen containing precipitate from step (i) with a solution containing at least 0.1M salt to obtain a fibrinogen enriched preparation.

Purification of fibrinogen

A method for the preparation of thrombin from a prothrombin-containing material is characterised in that the prothrombin-containing material is an activated prothrombin complex concentrate ActPCC fraction, which is contacted with divalent cations to convert the prothrombin to thrombin.

Method for the production of thrombin

Growing community of inventors

Victoria, Australia

Jerry Kanellos