Fisher Scientific Company

Jerry C Premus

Dennis A Gibboney

John T Schneider

David G Abichaker

Peter S Edwards

Lloyd Seager

A John Bertolino

Roger J Repasi

The present invention relates to an automatic slide staining system that will process stained slides, such as cytology or histology specimens. The invention includes a slide storage device, a slide transport apparatus, and a first platen including a plurality of staining stations. The stained slides are placed in the storage device and then are removed and processed at various stations via the transport apparatus. The invention can be altered so that a cover slip apparatus can be incorporated within the system. This permits a cover slip to be placed on the stained slide after a complete transverse of the slide staining stations.

Automated slide staining system and method thereof

A histological tissue specimen treatment process includes the steps of placing a plurality of histological tissue specimens to be processed in chamber structure, closing the chamber structure, monitoring the level of a first tissue processing material flowed into the chamber structure with a sensor system that responds to a characteristic of the first tissue processing material, terminating the flow of the first tissue processing material when the histological tissue specimens are immersed in the first tissue processing material, flowing the first tissue processing material from the chamber structure after the histological tissue specimens have been immersed in the first tissue processing material for a predetermined time interval, monitoring the level of a second tissue processing material flowed into the chamber structure with the sensor system in a changed sensitivity condition, terminating the flow of the second tissue processing material when the plurality of histological tissue specimens are immersed in the second tissue processing material, and flowing the second tissue processing material from the chamber structure after the plurality of histological tissue specimens have been immersed in the second tissue processing material for a predetermined time interval.

Process for histological tissue specimen treatment that includes

An improved method of potentiometrically titrating a sample to an unknown endpoint or endpoints is disclosed. The method includes delivering a titrant to the sample until an endpoint or endpoints are reached, while continuously monitoring the volume of the titrant delivered to the sample and continuously monitoring the potential of the sample during titration. The improvement in the method is accurately determining the endpoint or endpoints by establishing a substantially constant rate of change in sample potential during titration proximate to the endpoint or endpoints and maintaining the established rate of change in sample potential by adjusting the rate of delivery of the titrant.

Variable endpoint analyzer

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Scottdale, PA, United States of America

Jerry C Premus