Ep Technologies, Inc.

Covidien LP

Barrx Medical, Inc.

Other

Viveve, Inc.

Cardea Medsystems (tianjin) Co., Ltd.

University of California

United States Surgical Corporation

Tyco Healthcare Group LP

Newuro, B.v.

Calmedica, LLC

Jerome D Jackson

Roger Alan Stern

Stuart D Edwards

Patrick M Owens

Russell B Thompson

Thomas F Kordis

Vincent N Sullivan

Jennifer A Hodor

George H Smith

Roy D Corbitt

David K Swanson

Carson J Shellengberger

Dorin Panescu

James G Whayne

David S Utley

Ian F Smith

Thomas M Morse

Steven Marc Lopez

Stanley Levy

Jia Hua Xiao

Jonathan B Parmer

Sean Yasuo Sullivan

Patrick Karl Howe

Grant Michael Glaze

Jeffrey N Reynolds

Chun-Chih Cheng

Russell A Houser

Thomas M Bourne

Gloria Alvarez

Alan L Kaganov

Robert L Schmidlen

Ary S Chernomorsky

Sherree Leigh Lucas

Sidney D Fleischman

Michael D Lesh

Ingemar H Lundquist

David L McGee

Arye Rosen

Robert A Ganz

Omry Ben-Ezra

Brian D Zelickson

Itzhak Avneri

David R Staskin

Sheree Leigh Lucas

George A Ross

Terry E Spraker

Jack W Lasersohn

Carson J Shellenberger

Srihari Yamanoor

Russell Meirose

Donald I Galen

Benjamin Wang

Itzhak Averni

Grant M Glaze

This invention relates generally to apparatus and methods for tightening tissue of the female genitalia by heating targeted connective tissue with radiant energy, while cooling the mucosal epithelial surface over the target tissue to protect it from the heat. Embodiments include a handle and treatment tip that has both an energy delivery element and a cooling mechanism. The handle may be a two-handed handle allowing control even while rotating and maneuvering the treatment around the genital opening. The apparatus or system may also include an integrated controller, which may confirm tissue contact without applying RF energy, based only on the temperature of the applicator and the time since the last application of energy from the applicator.

Vaginal remodeling device and methods

Devices and methods are provided for treatment of tissue in a body lumen with an electrode deployment device. Embodiments typically include a device with a plurality of electrodes having a pre-selected electrode density arranged on the surface of a support. The support may comprise a non-distensible electrode backing that is spirally furled about an axis and coupled to an expansion member such as an inflatable elastic balloon. In some embodiments, the balloon is inflated to selectively expose a portion of the electrode surface while maintaining the electrode density.

Devices and methods for treatment of luminal tissue

An ablation apparatus places electrodes at the perimeter of a cavity. In an embodiment, the alternating electric field is used to expose the cavity to enough energy to ablate the cavity. In an embodiment, two modes are used to expose different regions of the cavity to different amounts of power for so that the thermal effect is more uniform. In an embodiment, the electrodes have a relatively large surface area so as to avoid charring the cavity, but are shaped so as to fit within a body orifice. For example, the diameter of the sheathed housing the electrodes during penetration may be only 5.5 mm.

Hollow body cavity ablation apparatus

An ablation apparatus places electrodes at the perimeter of a cavity. In an embodiment, the alternating electric field is used to expose the cavity to enough energy to ablate the cavity. In an embodiment, two modes are used to expose different regions of the cavity to different amounts of power so that the thermal effect is more uniform. In an embodiment, the electrodes have a relatively large surface area so as to avoid charring the cavity, but are shaped so as to fit within a body orifice.

Systems, devices, and methods to treat a urinary bladder are disclosed. An expandable member is introduced and expanded in the urinary bladder to appose one or more elongate conductors on the outer surface of the expandable member against the inner wall of the urinary bladder. The one or more elongate conductors are used to create a predetermined pattern of electrically isolated tissue regions having reduced electrical propagation such that electrical propagation through the urinary bladder as a whole is reduced. A mucus layer may be removed from the inner bladder wall prior to the ablation. Ablation may be regulated by impedance measurement with the one or more elongate conductors. The urinary bladder may be filled with a fluid to facilitate the impedance measurement.

Devices and methods for transurethral bladder partitioning

A system for measuring physiologic characteristics or treating tissue in a body lumen. The system may be used for treating abnormal mucosa in the esophagus. The system comprises an energy delivery device, such as an ablation device including an electrode support and an electrode pattern on the support. The ablation device may expand in size from a pre-deployed state to a deployed state. The system may include a sizing device having an inflatable balloon on a distal end of a catheter that is inflated with an expansion medium to expand the balloon to engage the wall of the esophagus so that the internal cross-section can be calculated or measured. The sizing device may also a controller for delivering an expansion medium and measuring the amount and pressure of the expansion medium inside the catheter. Methods of treating or diagnosing tissue are also disclosed.

Methods and systems for treatment of tissue in a body lumen

A method and apparatus for treating abnormal mucosa in the esophagus is disclosed, such that the depth of the treated tissue is controlled. The depth of ablation is controlled by monitoring the tissue impedance and/or the tissue temperature. A desired ablation depth is also achieved by controlling the energy density or power density, and the amount of time required for energy delivery. A method and apparatus is disclosed for measuring an inner diameter of a body lumen, where a balloon is inflated inside the body lumen at a fixed pressure.

Methods and systems for determining physiologic characteristics for treatment of the esophagus

This invention provides devices and methods for remodeling the female genital tissue, the device comprising a treatment tip, wherein the distal end of the treatment tip is conical, spherical, hemispherical, oval or circular in shape. The device further comprises one or more energy delivery elements for simultaneous cooling of the vaginal epithelium and transmission of energy for heating the tissues underneath the epithelium. In one embodiment, said device may further comprise one or more of the following: one or more temperature sensors for measuring the temperature at or below the epithelium; one or more directional sensors mounted on the hand piece or treatment tip; and one or more depth markers to show the depth of penetration of the treatment tip into the vagina. In another embodiment, this invention provides a device having a finger holder with electrodes for remodeling the female genital tissue.

Vaginal remodeling device and method

Growing community of inventors

Alexandria, VA, United States of America

Jerome D Jackson