Sanford Burnham Prebys Medical Discovery Institute

Jerold Chun

Ming-Hsiang Lee

Victoria Blaho

William J Romanow

Described herein are methods for identifying and measuring one or more non-classical variant(s) of amyloid precursor protein (APP) gene. Provided herein are methods for diagnosing and treating an individual having or suspected of having Alzheimer's disease following identification of an expression profile or an activity profile of the one or more non-classical variant(s).

Methods of diagnosing and treating Alzheimer's disease

Described herein are methods for inhibiting generation of one or more non-classical variant(s) of amyloid precursor protein (APP) gene. Provided herein are methods for diagnosing an individual having or suspected of having Alzheimer's-disease following identification of an expression profile or an activity profile of the one or more non-classical variant(s) and treating the individual using a reverse transcriptase inhibitor or salt thereof.

Growing community of inventors

La Jolla, CA, United States of America

Jerold Chun