Glaxosmithkline Biologicals Sa

Jeri Kay Sandvick

Kent Raymond Myers

Juan Jose Diaz Garcia

Chad Austin Farrenburg

Ahmad Taimour Baig

Jeb Yeatts Vandenburg

Lora Lea Lawrence

Felicie Georgette Colette Denet

Carine Berthe De Kesel

Saponin extracts containing at least 93% QS-21 main peak and 0.25-3% 2018 component by UV absorbance at 214 nm, methods for making said extracts, their use as vaccine adjuvants and related aspects.

Saponin purification

Crude aqueous extracts ofMolina containing at least the QS-21 main peak and 2018 component, wherein the ratio of 2018 component/QS-21 main peak is ≤0.075, as measured by UV absorbance at 214 nm, methods for obtaining such extracts and related aspects.

Saponin extraction

Crude aqueous extracts ofMolina containing at least the QS-21 main peak and 2018 component, wherein the ratio of 2018 component/QS-21 main peak is &#x2264;0.075, as measured by UV absorbance at 214 nm, methods for obtaining such extracts and related aspects.

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Hamilton, MT, United States of America

Jeri Kay Sandvick