Brownlee Labs, Inc.

Jeremy W Higgins

Robert R Brownlee

A replaceable cartridge column for use in high pressure liquid chromatograph pumping systems including a solid tube having a small bore therethrough carrying a packing material. The tube and terminated by a recess at each end which extends from the rim at the end of the tube inwardly and in communication with the bore. A plastic seal plug is disposed in the recess at each end to extend slightly beyond excess the length of the tube when so disposed and carries at its outer end a coaxial frit filter. The recess is provided with a flat bottom and the plastic plug has a corresponding bottom constructed to be positioned in face-to-face sealing opposition to fluid leakage and having further a flat sealing surface at its other end to engage a sealing surface of an end fitting of the liquid chromatographic pumping system and to provide a first, primary seal therewith independent of the rim of the column tube.

Cartridge for liquid chromatograph

A coupling for high pressure liquid chromatographic columns of any length, individually, or by union of two columns together, in which an end fitting carries a secondary seal together with internal means for retaining the seal in place. The end fitting is designed as a unitary assembly wherein the secondary seal is secured into the end fitting as a unitary assembly of parts without the use of screw threaded members. A special screw and nut configuration of end fittings permits the same design to be used for columns of extremely short lengths.

Growing community of inventors

Los Altos, CA, United States of America

Jeremy W Higgins