Arcus Biosciences, Inc.

Jeremy Thomas Andre Fournier

Jay Patrick Powers

Manmohan Reddy Leleti

Xuelei Yan

Kenneth Victor Lawson

Jenna Leigh Jeffrey

Joel Worley Beatty

Samuel Lawrie Drew

Guillaume Mata

Artur Karenovich Mailyan

Jaroslaw Kalisiak

Brandon Reid Rosen

Debashis Mandal

Erick Allen Lindsey

Yongli Su

Balint Gal

Anh Thu Tran

Steven Donald Jacob

Zhang Wang

Tezcan Guney

Kai Yu

Matthew Epplin

Clayton Hardman

Hyunyoung Moon

Karl T Haelsig

Dillon Harding Miles

Rhiannon Thomas-Tran

Ehesan Ui Sharif

Compounds that inhibit PI3Kγ, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by PI3Kγ.

2,3,5-trisubstituted pyrazolo[1,5-A]pyrimidine compounds

Compounds that inhibit HIF-2α, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by HIF-2α.

Tetralin and tetrahydroquinoline compounds as inhibitors of HIF-2alpha

Compounds that inhibit HIF-2&#x3b1;, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by HIF-2&#x3b1;.

Tetralin and tetrahydroquinoline compounds as inhibitors of HIF-2&#x3b1;

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Fremont, CA, United States of America

Jeremy Thomas Andre Fournier