Proteus Digital Health, Inc.

Otsuka Pharmaceutical Company, Limited

Other

Jeremy Frank

Benedict Costello

Robert Duck

Robert Azevedo

Peter Bjeletich

Hooman Hafezi

Mark Zdeblick

Eric Snyder

Iliya Pesic

George M Savage

Raymond H Schmidt

Kurt Scheinpflug

Chris Dong

Nikhil Pargaonkar

Hiren Patel

Nikolaus Leist

Timothy Robertson

Yashar Behzadi

Marc Jensen

David O'Reilly

Tariq Haniff

Olivier K Colliou

Lawrence W Arne

Todd Thompson

Robert L White

Vladimier Gelfandbein

Dino Lei

Bruce Addis

Benedict J Costello

Georgr M Savage

Various methods and apparatuses are presented for an ingestible capsule that includes a digital, ingestible sensor component&#x2014;or ingestible sensor&#x2014;embedded into the capsule. The ingestible sensor component may be configured to activate upon coming into contact with conductive fluid, such as a body's stomach fluid. Once activated, the ingestible sensor component may be configured to perform various tasks, such as transmitting one or more signals and obtaining biometric data about the body that ingested the capsule.

Methods for manufacturing capsules with ingestible event markers

The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can also measure the conditions of the environment surrounding the system.

Communication system with enhanced partial power source and method of manufacturing same

Ingestible event marker systems that include an ingestible event marker (i.e., an IEM) and a personal signal receiver are provided. Embodiments of the IEM include an identifier, which may or may not be present in a physiologically acceptable carrier. The identifier is characterized by being activated upon contact with a target internal physiological site of a body, such as digestive tract internal target site. The personal signal receiver is configured to be associated with a physiological location, e.g., inside of or on the body, and to receive a signal the IEM. During use, the IEM broadcasts a signal which is received by the personal signal receiver.

Ingestible event marker systems

Implantable hermetically sealed structures and methods for making the same. Devices, systems and kits including the hermetically sealed structures, as well as methods of using such devices and systems are included.

Implantable hermetically sealed structures

Methods for evaluating motion of a cardiac tissue location, e.g., heart wall, are provided. In the subject methods, timing of a signal obtain from a strain gauge stably associated with the tissue location of interest is employed to evaluate movement of the cardiac tissue location. Also provided are systems, devices and related compositions for practicing the subject methods. The subject methods and devices find use in a variety of different applications, including cardiac resynchronization therapy.

Cardiac motion characterization by strain measurement

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San Francisco, CA, United States of America

Jeremy Frank