University of Liverpool

Victoria Link Limited

Other

University of Glasgow

Jeremy E Turnbull

Peter Charles Tyler

Olga Vladimirovna Zubkova

Edwin Yates

Sophie Marie Thompson

Susannah Patey

Ralf Schwoerer

Scott Ernest Guimond

Andrew Munkacsi

Susan Carol Barnett

Jennifer Rosemary Higginson

The invention relates to dendritic compounds, the use of these compounds as pharmaceuticals, pharmaceutical and cosmeceutical compositions containing the compounds, and methods of treating cancer, inflammation, diabetic nephropathy, neurodegenerative disorders, Niemann-Pick Type C disease, or dermatological conditions.

Heparan sulfate glycomimetic compounds and their pharmaceutical and cosmeceutical uses

The present invention relates to the use of agents (including heparin derivatives) for the prevention and/or treatment of CNS damage.

Agents for the prevention and/or treatment of central nervous system damage

The invention relates to dendritic compounds, the use of these compounds as pharmaceuticals, pharmaceutical compositions containing the compounds, processes for preparing the compounds, and methods of treating diseases or conditions in which it is desirable to inhibit &#x3b2;-secretase.

Saccharide dendritic cluster compounds as inhibitors of BACE-1

The invention relates generally to oligosaccharide compounds and the use of these compounds as pharmaceuticals for treating diseases or conditions in which it is desirable to inhibit &#x3b2;-secretase.

Oligosaccharide compounds

A pharmaceutical composition for use in the prevention and/or treatment of a neurodegenerative disorder comprising a compound comprised of one or more disaccharide units, the or each disaccharide unit comprising a uronate moiety linked to a glucosamine moiety, wherein the 2-O atom of the uronate moiety is substituted with a hydrogen atom, the 6-O atom of the glucosamine moiety is substituted with a sulphate group and the 2-N atom of the glucosamine moiety is substituted with an atom or group other than a sulphate group. The composition is particularly preferred for use in the prevention and/or treatment of Alzheimer's disease.

Prevention and/or treatment of neurodegenerative disorders

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Nr Cleobury Mortimer Shropshite, United Kingdom

Jeremy E Turnbull