Research Development Foundation

Clayton Foundation for Research

Jere W McBride

David H Walker

Christopher Kuyler Doyle

Tian Luo

Xue-Jie Yu

Christopher K Doyle

Immunoreactive engineered polypeptides are provided. The engineered polypeptides can be used to diagnose or induce an immune response againstor

Immunoreactive peptides

Provided herein are chimeric polypeptides that may be used, e.g., for the diagnosis of or vaccination againstand/or

Chimeric immunogenic polypeptides

The present invention concerns gp36 immunoreactive compositions forand gp 47 immunoreactive compositions for. In particular, epitopes forgp36 andgp 47 are disclosed. In certain embodiments, the immunoreactive compositions comprise tandem repeats having carbohydrate moieties.

Immunoreactive protein orthologs ofand

The present invention concerns VLPT immunoreactive compositions forand compositions related thereto, including vaccines, antibodies, polypeptides, peptides, and polynucleotides. In particular, epitopes forVLPT are disclosed.

Vaccines and diagnostics for the ehrlichioses

The present invention concerns gp19 immunoreactive compositions forand compositions related thereto, including vaccines, antibodies, polypeptides, peptides, and polynucleotides. In particular, epitopes forgp19 are disclosed.

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The present invention concerns gp36 immunoreactive compositions for E. canis and gp 47 immunoreactive compositions for E. chaffeensis. In particular, epitopes for E. canis gp36 and E. chaffeensis gp 47 are disclosed. In certain embodiments, the immunoreactive compositions comprise tandem repeats having carbohydrate moieties.

Provided herein are immunoreactive peptides which can selectively bind-specific anti-p120 or anti-p140 antibodies. Methods and kits utilizing the immunoreactive peptides are also provided. The immunoreactive peptides may be utilized, e.g., for determining whether or not a subject is infected withor. In certain embodiments, the immunoreactive peptides may be utilized in an ELISA or lateral flow assay.

Growing community of inventors

League City, TX, United States of America

Jere W McBride