Aprogen Inc.

Kumho Ht, Inc.

Aprogen Medicines Inc.

Jeong Won Hong

Sangsoon Yoon

Eun Jung Kim

Yoo Ri Moon

Da Bin Choi

Gil Yong Ji

Hyung-Geun Song

Soseul Kim

The present invention relates to an antibody or an antigen-binding fragment thereof specifically binding to CD66c which is expressed in myeloid-derived suppressor cell (MDSC) and a use thereof, and specifically to an antibody or an antigen-binding fragment thereof specifically binding to CD66c, a pharmaceutical composition or a diagnosing composition including the same. The anti-CD66c antibody of the present invention can be used usefully for the treatment of various diseases by targeting MDSC which can induce the immunosuppression.

Use for preventing and treating myeloid-derived suppressor cell-related diseases

Provided is an antibody that recognizes and binds to carbonic anhydrase or antigen-binding fragment, a nucleic acid molecule coding for the antibody or antigen-binding fragment, a vector carrying the nucleic acid molecule, a host cell including the nucleic acid molecule or the vector, and use of the antibody or antigen-binding fragment thereof in the alleviation, prevention, treatment or diagnosis of solid cancers.

Antibody binding to carbonic anhydrase and use thereof

Growing community of inventors

Seoul, South Korea

Jeong Won Hong