Advanced Cardiovascular Systems, Inc.

Abbott Cardiovascular Systems, Inc.

Other

Jeong Soo Lee

David C Gale

Kenneth L Wantink

Ketan P Muni

Bin Huang

John Arthur Simpson

Timothy A Limon

Edwin Wang

Roseminda J White

Bridget A Hurley

Mina W B Chow

Paul M Consigny

David H Burkett

Florencia Lim

Robert D Ainsworth

Deborah L Kilpatrick

Jeffrey T Ellis

Charles David Claude

Emmanuel C Biagtan

Fozan El-Nounou

Chi Le Long

William Earl Webler, Jr

Udayan G Patel

Anthony J Abbate

Stephen J Tiernan

Alan A Tannier

Thomas Haslinger

Neftali Fernandez

Tim Kitchen

Fortino Vasquez Flores

Murthy V Simhambhatla

Stephen G Schaible

Timoteo J Tomas

Tung-Liang Lin

Ken Wantink

Tim Geiser

Sandra K Schenk

Terry Freeman

Cheri Stiger

Jose A Romero

Carolyn Voyles

Evgenia Mandrusov

Marc Mehrzad Jalisi

Bruce M Wilson

Klaus Kleine

Srinivasan Sridharan

Justin K Mann

Barbara E Stamberg

Tai Chun Cheng

Richard T Thornton

Gene Michal

Robert P Saltman

John Schreiner

Florian Niklas Ludwig

Cheryl Rice

Gabriel Asongwe

Vincent Bavaro

Fernando Gonzalez

Marc L Speck

Ziyun Chen

Vidya J Nayak

Ken Bueche

Sharon Wong

Delma M Blankenship

Matthew James Chludzinski

Joseph J Sciacca

Mary B Michaels

John Eric Henckel

Fidel Albert Urrabazo

Daniel Wiegand

Christopher McMurtry

Cheryl Stiger

Gary Heinemann

Christine Gutting

Portino Vasques Flores

Forencia Lim

Syed FA Hossainy

Emmanuel Biagtan

Joe Callol

Balloon catheter includes an outer shaft including a hypotube and a monolithic multilayer distal outer member and having an inflation lumen defined therethrough, a balloon in fluid communication with the inflation lumen, and an inner tubular member having a guidewire lumen defined therethrough. The monolithic multilayer distal outer member has a proximal end portion and a distal end portion. The monolithic multilayer distal outer member has an inner layer comprising a first polymer having a tensile strength greater than about 8,000 psi and an outer layer comprising a second polymer having a flexural modulus of less than about 130,000 psi at room temperature. A proximal end of the monolithic multilayer distal outer member is coupled to the hypotube. The monolithic multilayer distal outer member is necked to a reduced diameter along at least a portion of a length thereof. The balloon has a proximal balloon shaft coupled to a distal end of the monolithic multilayer distal outer member. The inner tubular member extends distally from a proximal port in the proximal end portion of the monolithic multilayer distal outer member through at least a portion of the balloon.

Catheter having monolithic multilayer distal outer member

A catheter having an multilayered shaft section with a first layer formed of a polyimide first material and a second layer formed of a second material. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. However, in alternative embodiments, a thermoplastic polyimide is used. The thermoset polyimide has a very high glass transition temperature (Tg) of approximately 400&#xb0; C. (as measured by differential scanning calorimetry), and excellent dimensional stability at the processing temperature of polyamides commonly used in catheter components. As a result, during formation and assembly of the catheter, production of a thin polyimide layer with controlled dimensions is facilitated. The polyimide has a high modulus and provides a thin walled yet highly pushable shaft section, while the second layer provides kink resistance. In one embodiment, the second material is selected from the group consisting of a polyamide material and a polyurethane material.

Catheter with a multilayered shaft section having a polyimide layer

Balloon catheter comprises an elongate catheter shaft having a proximal section, a distal section, and an inflation lumen defined therein and a multilayer balloon on the distal section of the shaft comprising a first layer made of a first polymer material having a first Shore durometer hardness, a second layer made of a second polymer material having a second Shore durometer hardness greater than the first Shore durometer hardness, wherein the second layer is an inner layer relative to the first layer, and a third layer made of a third polymer material having a third Shore durometer hardness less the first Shore durometer hardness, wherein the third layer is an inner layer relative to the second layer. Method of making a balloon catheter is also provided.

Multilayer balloon for a catheter

A multilayer balloon catheter is formed to have an inner layer and an outer layer, where the outer layer is adapted to resist shredding and premature rupture. The outer layer is formed of a material having a glass transition temperature that is lower than the transition or melting temperature of the inner layer. By forming the balloon on a mold at a temperature between the glass transition temperature of the outer layer and the glass transition or melting temperature of the inner layer, the outer layer will undergo a thermal relaxation that will alleviate some of the axial orientation of the polymer chains that develop during the formation of the multilayer balloon. This relaxation leads to a resistance to shredding when the balloon is expanded during operation.

Robust multi-layer balloon

A balloon catheter having a soft distal tip member having a non-tacky inner (liner) layer material and a soft flexible outer layer material, with both materials being readily thermally bondable to the catheter balloon.

Catheter having a readily bondable multilayer soft tip

Elongate, flexible catheter includes a shaft having a proximal end, a distal end, and a lumen extending therein. The shaft has an inner layer comprising an amorphous polyamide having a Shore D durometer value of greater than 78, and an outer layer comprising a semi-crystalline polyamide or copolyamide having a Shore D durometer value of less than 76. The outer layer is thinner than the inner layer. The shaft has an increased resistance to kinking as compared to a similar shaft of a single layer of the amorphous polyamide having a Shore D durometer value of greater than 78.

Robust catheter tubing

A balloon catheter having a multilayer catheter shaft is formed to have an inner layer and an outer layer, where the inner layer and outer layer are selected from materials that enhance the pushability of the catheter while preserving the flexibility. Using a combination of a high Shore D duromater value material and a lower Shore D duromater value material, various combinations of multilayer catheter shafts are disclosed utilizing different glass transition temperatures and block copolyamides to obtain the desired characteristics.

A golf putter practice device for practicing repetitive ball striking develops consistent contact on an optimal position on the striking surface of a putter. The device includes a body having a top surface, a front surface, and a channel extending through the body. The channel receives a flange of the putter therein whereby the front surface of the body covers a striking surface of the putter. Alignment indicia transverse to the channel is positioned on the top surface of the body. The alignment indicia has a front section abutting and extending rearwardly from a junction of the top surface with the front surface. A fastener is coupled to the body for securing the body on the putter.

Golf putter practice device

Multilayer balloon for a catheter comprises a first layer made of a first polymer material having a first Shore durometer hardness, a second layer made of a second polymer material having a second Shore durometer hardness greater than the first Shore durometer hardness, wherein the second layer is an inner layer relative to the first layer, and a third layer made of a third polymer material having a third Shore durometer hardness less the first Shore durometer hardness, wherein the third layer is an inner layer relative to the second layer. Method of making a multilayer balloon for a catheter and a balloon catheter are also provided.

A catheter having an elongated shaft which has a multilayered distal tip with a first layer formed of a polyimide first material and a second layer formed of a polymeric second material. In one embodiment the multilayered distal tip is a separate member, distal to the distal end of a proximal portion of the shaft. In another embodiment, the shaft has an outer tubular member, and a multilayered inner tubular member with a distal end which forms the multilayered distal tip of the shaft. In a presently preferred embodiment, the polyimide material is a thermoset polyimide. In one embodiment, the polymeric second material is a polyamide material.

Catheter with a polymide distal tip

Method for fabricating a balloon catheter including providing an inner tubular member having a distal section and a distal end with a lumen extending therein and forming a balloon having a distal leg with a first segment having a first diameter and a first wall thickness and a second segment having a second wall thickness. The second diameter is greater than the first diameter and the first wall thickness is greater than the second wall thickness. The distal end section of the inner tubular member can be positioned in the balloon and bonded to the first segment while reducing the diameter of the second segment. Method also provided for fabricating a multilayer balloon catheter including removing at least a portion of an outer layer from the distal leg of the balloon.

Soft tip balloon catheter

Methods for forming a 'coating gradient' on medical devices, such as a balloon catheter or guidewire are disclosed. The balloon portion of the catheter has a protective covering initially placed over it to prevent the balloon from receiving a first hydrophilic coating. After a first hydrophilic coating is applied, the protective covering is removed. A second hydrophilic coating could be applied to the catheter. A guidewire having less lubricity at the distal end portion also can be created. A first hydrophilic coating is applied to the elongated shaft and distal shaft section of the guidewire. After the first hydrophilic coating cures, the first hydrophilic coating is removed from a portion of the distal shaft section of the guidewire. A second hydrophillic coating can then be applied to the elongated shaft and distal shaft section of the guidewire. The second hydrophilic coating can be allowed to cure.

Manufacturing processes for making medical devices having a coating gradient

Engraftment of therapeutic cells and agents to a target site in an organism is enhanced by mechanical, chemical and biological methods and systems.

Intracoronary device and method of use thereof

The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.

Implantable device having a coating comprising carrageenan and a biostable polymer

Growing community of inventors

Diamond Bar, CA, United States of America

Jeong Soo Lee