Seoul National University

Intellectual Discovery Co., Ltd.

Other

Yonsei University

Korea Institute of Science and Technology

Korea Research Institute of Standards and Science

Goldstar, Co., Ltd.

Samsung Electronics Co., Ltd.

Hyundai Motor Company

Kia Corporation

Osong Medical Innovation Foundation, Korea University Research and Business Foundation

Postech Academy-industry Foundation

Snu Rdb Foundation

Ewha University-Industry Collaboration Foundation

Samsung Life Public Welfare Foundation

Jeong Hun Kim

Dong Hyun Jo

Eun Kyoung Kim

Tae Geol Lee

Jung Hyun Kim

Sung Hyun Kim

Sung Wook Park

Ji-Won Son

Man Soo Choi

Hyoungchul Kim

Yi Yong Baek

Dong Woo Song

Jong Hak Kim

Sung Soo Shin

Won Jin Park

Kyu Beom Hwang

Ki Cheol Jang

Chi Hyun Park

Young Myeong Kim

Byeong Gwan Kim

Jong Kwan Koh

Jong Beom Na

Jin-Soo Kim

Ji Won Son

Jong Ho Lee

Seung Yong Lee

Jong Hee Han

Jung Min Lee

Ho-Young Reho Lee

Soohyun Kim

Han Soo Kim

Junho Chung

Sung Won Yoon

Byung Kook Kim

Byung Joo Lee

Jong Bae Kim

Won Jong Kim

Eun Kyung Hong

Hyoung Chul Kim

Sang Won Seo

Hun Gi Jung

Hyun Ok Kim

Hyori Kim

Hae Weon Lee

Young-Ger Suh

Sang Geon Kim

Jae H Chung

Seokjoong Kim

Sung Jun Choi

Sun Hyoung Choi

Choon Woo Kim

Kyu-Won Kim

Young Jung Kim

Eui Y Oh

Dong Chul Kim

Seungbeom Lee

Young Bok Han

Jun Kyung Seong

Jae Hyun Choi

Kyung Rim Kim

Jin Suck Suh

June Seok Heo

Hae Ryoung Kim

Jae Moon Yang

Young S Park

Hong K Kyung

Hyun Gil Shin

Kyung Tae Kim

Yoo Chan Hong

Seung Cheol Kang

Seung Yeon Hwang

Wo Dum Jung

Hongchan An

Young Jip Kim

Kyoungmi Kim

Sun Hwa Choi

Jeong J Mun

Jong Yeon Kim

Ui Y Oh

Jae Han Lee

Un Gi Kim

Sihyeon Kim

Suree Kim

Dongmin Kang

Dobeen Hwang

Min Seong Kim

Ri Mi Lee

Jung Mok You

Won Seok Cho

Jihyun Lee

Tea Hoon Park

The present invention relates to an apparatus for predicting a region-specific cerebral cortical contraction rate on the basis of a CT image. The present invention may comprise: a deep learning step of a deep learning network learning, by selecting and using CT images of a plurality of patients and segmentation information thereof, a correlation between the CT images and the segmentation information; a feature extraction step of extracting, on the basis of each piece of the segmentation information, semantic feature information corresponding to the CT images; a machine learning step of a machine learning model learning, after a plurality of region-specific cerebral cortical contraction rates corresponding to each piece of the semantic feature information are additionally acquired, a correlation between the semantic feature information and the region-specific cerebral cortical contraction rates; a segmentation step of, when an image to be analyzed is input, acquiring segmentation information corresponding to the image to be analyzed, through the deep learning network; and a prediction step of predicting and reporting, after semantic feature information corresponding to the image to be analyzed is extracted on the basis of the segmentation information, a region-specific cerebral cortical contraction rate corresponding to the semantic feature information through the machine learning model.

Method and apparatus for predicting region-specific cerebral cortical contraction rate on basis of CT image

An autonomous driving apparatus and a method for generating a precise map using the autonomous driving apparatus are configured to vary an application ratio of interpolation to precise map data to be stored depending on an accident risk on a corresponding road and a distance from a host vehicle during driving so as to optimize the precise map data to be stored. The autonomous driving apparatus includes an accident risk classification unit configured to vary the application ratio of interpolation to data and whether or not to store data acquired by applying interpolation to the data depending on the accident risk on the corresponding road and the distance from the host vehicle during driving, and an autonomous driving controller configured to generate the precise map data depending on the accident risk classification unit.

Autonomous driving apparatus and method for generating precise map

The present invention relates to an antibody against a PDGF receptor, an antibody-drug conjugate in which a chemotherapeutic agent is conjugated to the antibody against PDGF receptor, and a use of prevention or treatment of ocular neovascular diseases.

PDGF receptor antibody and use thereof

The present invention relates to an artificially manipulated neovascularization-associated factor for regulating neovascularization and a use thereof. More particularly, the present invention relates to a system for artificially regulating neovascularization, which includes an artificially manipulated neovascularization-associated factor for regulating neovascularization and/or a composition for artificially manipulating the neovascularization-associated factor. In a specific aspect, a neovascularization regulatory system including a neovascularization-associated factor such as artificially manipulated VEGFA, HIF1A, ANGPT2, EPAS1, or ANGPTL4 and/or an expression product thereof is provided.

Artificially-manipulated neovascularization regulatory system

The present invention relates to a composition for gene manipulation for treating or improving a retinal dysfunction disease or a method using the same. More particularly, the present invention relates to a composition for gene manipulation including a guide nucleic acid capable of targeting a retinal function-forming gene and a method of treating or improving a disease caused by retinal dysfunction by artificially manipulating and/or correcting a retinal function-forming gene using the same.

Gene manipulation for treatment of retinal dysfunction disorder

Disclosed are improved peptides for inhibiting angiogenesis, Ac-RLYE (SEQ ID NO: 1) and R(D)LYE (SEQ ID NO: 6), and a composition for the prevention and treatment of cancers and diseases related to angiogenesis comprising the peptides as an active ingredient. A peptide for inhibiting angiogenesis is disclosed wherein the L-Arg of an N-terminal is acetylated in a peptide consisting of an amino acid sequence of Arg-Leu-Tyr-Glu (SEQ ID NO: 1). A peptide for inhibiting angiogenesis is disclosed wherein L-Arg is substituted with D-Arg in a peptide consisting of the amino acid sequence of Arg-Leu-Tyr-Glu (SEQ ID NO: 6). Methods for using a composition comprising the peptides as active ingredients for the prevention or treatment of diseases (cancer, diabetic retinopathy or senile macular degeneration) caused by excessive angiogenesis are also disclosed. The peptides have a long half-life and are excellent in VEGF-induced angiogenesis inhibitory effect.

Angiogenesis-inhibiting peptide and composition for preventing and treating angiogenesis-related disease comprising same as active ingredient

Swimming assistance apparatus

The present invention presents a method for manufacturing a negative electrode of a solid oxide cell in a three-dimensional structure by using a pressurization process. In addition, the present invention proposes a structure in which the entire interface of a solid oxide cell is manufactured on the manufactured three-dimensional negative electrode substrate, through various deposition methods, in a three-dimensional structure so as to maximize a reaction area.

Method for manufacturing solid oxide cell having three-dimensional ceramic composite interface structure

Disclosed is a swimming assistance apparatus, which is worn on a user's both feet to provide the user with buoyancy, such that the user can float on water and swim in a good swimming style while repeatedly moving the waist from side to side like a fish, thereby reinforcing the user's waist muscles. Persons who have knee joint arthralgia or backache or persons who have disability in the lower body can use the swimming assistance apparatus for medical purposes, such as pain relief or treatment.

The present invention relates to a method for producing dextran polymer-based amplified nucleic acid aptamer nanoconstructs which efficiently and selectively capture a specific target molecule, the method comprising linking a short nucleic acid sequence or a complementary sequence for formation of nanoconstructs and a nucleic acid aptamer sequence for capture of the specific target molecule to a dextran polymer by a chemical reaction, mixing the resulting polymer/nucleic acid substances with each other to form nanostructures, subjecting the nanostructures to rolling circle amplification, thereby forming a nucleic acid aptamer having a repeated structure. The dextran polymer-based amplified nucleic acid aptamer nanoconstructs have the effect of efficiently and selectively capturing a specific target molecule.

Method for producing dextran polymer-based, amplified nucleic acid aptamer nanoconstruct selectively capturing target molecule

Disclosed is a method for infiltrating a porous structure with a precursor solution by means of humidification. The infiltration method with a precursor solution using moisture control comprises the steps of: (S1) providing a substrate having porous structures deposited thereon; (S2) depositing, by electrospraying, a precursor solution on the substrate having porous structures deposited thereon; (S3) humidifying the porous structures having the precursor solution deposited thereon; and (S4) sintering the humidified porous structures.

Method for infiltrating with precursor solution using moisture control

Provided are a method of preventing and/or treating an eye disease, using a Cas9 protein and a guide RNA targeting VEGF-A, and a ribonucleoprotein including a Cas9 protein and a guide RNA targeting VEGF-A.

Method of treating or preventing eye disease using Cas9 protein and guide RNA

Disclosed are conjugated polymer nanoparticles and a method of producing the same. The conjugated polymer nanoparticles include a conjugated polymer, fatty acid and an amphiphile polymer. The conjugated polymer nanoparticles can be doped even under a neutral environment, thus exhibiting high electrical conductivity and exerting absorbance properties in the near-infrared band even under a neutral environment such as in vivo.

Conjugated polymer nanoparticles and manufacturing method thereof

Provided is a method for screening drugs, more particularly, a method for screening drugs by measuring capacitance of an endothelial cell layer at a frequency region of 100 Hz to 5 kHz to screen a drug affecting paracellular permeability of the endothelial cell layer or a drug penetrating through a paracellular path.

Method of screening drugs

Growing community of inventors

Seoul, South Korea

Jeong Hun Kim