Cosmax Nbt, Inc.

Cosmax Ns, Inc.

Yonsei University

Jeong Ho Geum

Jin Hak Kim

Su Young Choi

Chang Hee Kim

Jae Kwan Hwang

Mi Bo Kim

Joon Hyung Lee

Ji Hwan Jang

Min Son Kweon

Hye Rim Kim

Jun Gon Yun

Do Wan Kwon

Theand licorice complex mixture of the present invention has the synergy effects for the efficacies of reducing cough through inhibition of TRPV1 activity, reducing lung inflammation through inhibition of CXCR1 and CXCR2 activities and GR-1+CD11b+ cell ratio reduction, and suppressing sputum production through inhibition of MUC5AC activity and therefore it can be widely utilized as a composition for the prevention or treatment of respiratory diseases.

Composition for the prevention or treatment of respiratory diseases caused by fine dust comprisingand licorice extract

The present invention relates to a composition for preventing or treating a muscle disorder, which includes a chrysanthemum extract or 3,5-dicaffeoylquinic acid as an active ingredient, and specifically, it may be used to reduce mRNA expression of atrogin-1 and MuRF1, which are main biomarkers involved in muscle protein degradation and increase mRNA expression of the mTOR protein, which is a main biomarker involved in muscle protein formation, and myogenin and MyoD, which are biomarkers related to muscle differentiation, thereby reducing muscle loss, and thus the chrysanthemum extract or 3,5-dicaffeoylquinic acid can be used in prevention and treatment of a muscle disorder, or improvement in muscle function. In addition, the chrysanthemum extract or 3,5-dicaffeoylquinic acid increases the activity of SIRT1 and PGC-1&#x3b1;, which are the main biomarkers involved in exercise performance, thereby excellently enhancing exercise performance. In addition, the present invention is a natural substance and may be safely used without a side effect, and therefore may be used as a medication, food or a cosmetic.

Composition for improvement of muscle function containing 3,5-dicaffeoylquinic acid or chrysanthemum extract

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Seoul, South Korea

Jeong Ho Geum