The University of British Columbia

Jens Huft

Carl Lars Genghis Hansen

Pieter Rutter Cullis

Andre Wild

Nathan Maurice Belliveau

David E Walker

Sohrab Shah

Hans Zahn

Bill Kengli Lin

Anders Klaus

Samuel Alves Jana Rodrigues Aparicio

Kaston Leung

Adi Steif

Stuart Malcolm

Ismail Hafez

Marinus Theodorus Johannes Van Loenhout

Alex Leung

Robert James Taylor

James R Taylor

Sohrab Prakash Shah

Methods, devices and systems for analyzing precious samples of cells, including single cells are provided. The methods, devices, and systems in various embodiments of the invention are used to assess genomic heterogeneity, which has been recognized as a central feature of many cancers and plays a critical role in disease initiation, progression, and response to treatment. The methods devices and systems are also used to analyze embryonic biopsies for preimplantation genetic diagnosis (PGD). In one embodiment, the devices, systems and methods provided herein allow for the construction of genomic and RNA-seq libraries without a pre-amplification step.

Methods for analyzing genomic variation within cells

Lipid particles containing a nucleic acid, devices and methods for making the lipid particles, and methods for using the lipid particles.

Nucleic acid-containing lipid particles and related methods

Growing community of inventors

Marburg, Germany

Jens Huft