Richter Gedeon Vegyeszeti Gyar Rt

Jeno Kobor

Laszlo Szporny

Eva Palosi

Gyorgy Hajos

Elemer Ezer

Gabor Bernath

Laszlo Denes

Ferenc Fulop

Gabor Motika

Pal Sohar

Alajos Kalman

Janos Lazar

Ferenc Folop

Pal Perjesi

Attila Sohajda

The invention relates to new 1-[6-(2'-substituted-5', 6', 7', 8'-tetrahydro-4'-oxo-quinazolino)]-3,4-dihydro-6,7-disubstituted-isoquinol ine derivatives of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 each independently represents hdyroxyl or alkoxy having from 1 to 6 carbon atoms,

1-(6-(2'-substiuted-5', 6', 7',

The invention relates to new N-substituted bis(hydroxymethyl)-methyl-isoquinoline derivatives of the formula (I), ##STR1## wherein R.sup.1 and R.sup.2 represent hydroxyl or alkoxy having from 1 to 6 carbon atoms,

N-substituted isoquinoline derivatives and pharmaceutical compositions

The invention relates to new 1-[bis(hydroxymethyl)-methyl]-3,4-dihydro- or -1,2,3,4-tetrahydroisoquinoline derivatives of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 represent hydroxyl or alkoxy having from 1 to 6 carbon atoms,

Isoquinoline derivatives, and pharmaceutical compositions containing them

The invention relates to new bis(substituted methyl)-methyl-isoquinoline derivatives of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 represent hydroxyl or alkoxy having from 1 to 6 carbon atoms,

Bis(substituted methyl)-methyl-isoquinoline derivatives and

The invention relates to new [1,3]oxazino[4,3-a]-isoquinoline derivatives of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 represent hydroxyl or alkoxy having from 1 to 6 carbon atoms,

[1,3]oxazino[4,3-a]-isoquinoline derivatives and pharmaceutical

The invention relates to new 1-cyclohexyl-3,4-dihydroisoquinoline derivatives of the formula (I) ##STR1## wherein R.sup.1 and R.sup.2 each independently represents hydrogen, hydroxyl or alkoxy having from 1 to 6 carbon atoms,

1-cyclohexyl-3,4-dihydroisoquinoline derivatives and pharmaceutical

The invention relates to new 2H-azeto[2,1-a]isoquinoline derivatives of formula (I) ##STR1## wherein R.sup.1 and R.sup.2 represent hydroxyl or alkoxy having from 1 to 6 carbon atoms,

2H-azeto[2,1-a]-isoquinoline derivatives and pharmaceutical compositions

The invention relates to 1-(hydroxymethyl)-1,6,7,11b-tetrahydro-2H,4H-[1,3]oxazino- or -thiazino-[4,3-a]isoquinoline derivatives of the formula (I), ##STR1## wherein R.sup.1 and R.sup.2 are alkoxy having from 1 to 6 carbon atoms,

Growing community of inventors

Szeged, Hungary

Jeno Kobor