Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Jeno Ghyczy

Gyorgy Csermely

Sandor Szoke

Gyorgy Lugosi

Maria Bakonyi

Gy/o/ Rgy Lugosi

S/a/ Ndor Sz/o/ Ke

M/a/ Ria Bakonyi

Gy/o/ Rgy Csermely

The invention concerns a new process for the preparation of biologically active 2-[(alkoxycarbonyl)amino]-5-(alkylthio)-1H-benzimidazoles of the formula (V) ##STR1## wherein R and R.sup.1 independently stand for alkyl having 1 to 3 carbon atoms. According to the invention compounds of the formula (V) are prepared by reacting carbamic acid alkyl esters of the formula (I) ##STR2## wherein R is as defined above, with (a) chlorosulfonic acid or

Preparation of alkylthiobenzimidazoles

The invention concerns a new process for the preparation of biologically active 2-[(alkoxycarbonyl)amino]-5-(alkylthio)-1H-benzimidazoles of the general formula (V) ##STR1## wherein R and R.sup.1 independently stand for alkyl having 1 to 3 carbon atoms.

Process for preparing alkylthiobenzimidazoles

This invention relates to a process for the preparation of aluminum alloys having a high reducing capacity for use in reductions in organic chemistry. According to this method a discontinuous heterodisperse superficial alloy is formed by subjecting an aluminum alloy prepared by a metallurgical process to superficial activation and/or treating aluminum with a salt of a metal having a greater normal electrode potential than that of aluminum; whereby the solution of said metal in a protic solvent is reacted with granular aluminum and/or an aluminum alloy. The catalyst prepared according to the invention is especially suitable for the reduction of a nitro or nitroso group into an amino group. The aluminum alloys having a high reducing capacity are also within the scope of the invention.

Aluminum alloys having a high reducing capacity and preparation thereof

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Budapest, Hungary

Jeno Ghyczy