Kpmg Llp

The Rockefeller University

Jenny Li

David Richard Jarczyk

Nikola G Ognjanovic

Michal Pol

Steven K Rainey

Rafiq Mohamed Jalal

Ashish Lal Rajbanshi

Noah Leuthaeuser

Christopher Donnelly

Thomas Tuschl

Klaas Max

Karl Bertram

Kemal Akat

Kimberly Bogardus

Brian Chew

The invention relates to systems and methods for providing modular and configurable smart contracts for blockchain applications. The smart contracts may be utilized to retain all transaction attribute values in a world state database of the blockchain-implemented ledger. The systems and methods can further provide for dynamically configurable metadata and rules for transaction attributes recorded on a blockchain transaction log. The metadata and rules corresponding to the transaction attributes may be dynamically updated and applied to the transaction attributes.

Modular, configurable smart contracts for blockchain transaction processing

An embodiment of the present invention is directed to a fully self-sufficient and configurable smart contract for private blockchains that eliminates code and updates. An embodiment of the present invention does not rely on multiple smart contracts to handle incoming transactions and data. A configurable smart contract framework of an embodiment of the present invention enables end users to configure and manage various business rules to be applied to transaction data without the need to write smart contract code. These business rules may be stored in the ledger in the form of transaction configuration rules and query presets for full auditability and traceability.

Configurable smart contract platform

The invention relates to systems and methods for providing modular and configurable smart contracts for blockchain applications. The smart contracts may be utilized to retain all transaction attribute values in a world state database of the blockchain-implemented ledger. The systems and methods can further provide for dynamically configurable validation metadata and validation rules for transaction attributes recorded on a blockchain transaction log. The validation metadata and validation rules corresponding to the transaction attributes can be dynamically updated and applied to the transaction attributes to validate or invalidate a transaction.

Modular, configurable smart contracts for blockchain transaction processing validations

Modular, configurable smart contracts for blockchain transactions

The disclosure provides methods for isolating nucleic acids from a biological fluid. In one aspect, the disclosure provides a method for isolating RNA. In another aspect, the disclosure provides a method for isolating DNA. In one aspect, the methods described herein utilize a protocol that combines a detergent-based initial denaturation, protease digestion, and organic extraction followed by column purification that maximizes RNA/DNA yield and preserves RNA/DNA integrity. In yet another aspect, the disclosure provides a kit for isolating RNA and/or DNA.

Method of RNA isolation from clinical samples

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New York, NY, United States of America

Jenny Li