University of California

Cz Biohub Sf, Llc.

Synarc Inc

Jenny Folkesson

Mads Nielsen

Claus Christiansen

Joseph L DeRisi

Erik B Dam

Paola Pettersen

Paul Lebel

Ole F Olsen

Rafael Gomez-Sjoberg

A method of measuring malarial parasitemia includes disposing a sample including red blood cells in liquid form on a sample stage, illuminating the sample with optical radiation, capturing a plurality of images of the sample, and extracting, from the one or more of the plurality of images, a set of red blood cell images. Each red blood cell image is associated with a particular red blood cell. The method also includes for each red blood cell image in the set of red blood cell images, inputting each red blood cell image into a machine learning model and generating, using the machine learning model, a classification related to a malaria parasite lifecycle stage for each of the red blood cells. The method further includes determining the malarial parasitemia for the sample.

Method for label-free imaging and classification of malaria parasites

A method for the analysis of three dimensional scan data representing an articular cartilage is provided to extract a quantitative parameter indicative of joint pathology. A measure of local curvature of the cartilage is determined within a region of interest. The value of the quantitative parameter of this joint derived from this measure is compared with the value of a similar quantitative parameter previously established in respect of healthy joints and/or joints characterized by a pathology.

Cartilage curvature

Growing community of inventors

San Francisco, CA, United States of America

Jenny Folkesson