Illumina Corporation

Jennifer Wang

Craig M Ciesla

Steven Mark Barnard

Dietrich A Dehlinger

Ali Agah

Aathavan Karunakaran

Arnaud Rival

Fabien Abeille

Murali Venkatesan

Pargol Gheissari

A method for reducing sequencing by synthesis cycle time using a microfluidic device is provided. The microfluidic device comprises a flow cell having an inlet port, an outlet port, and a flow channel extending between the inlet port and the outlet port, wherein the flow channel receives an analyte of interest and one or more reagents for analyzing and detecting molecules. To aid in the acceleration of the reactions, the microfluidic device comprises a mixing device to increase the rates of diffusion of the reagents from the fluid bulk to an active surface of the flow cell. The mixing device comprises at least one of an electrothermal mixing device, an active mechanical mixing device, and a vibrational mixing device.

Methods and devices for mixing in a microfluidic system

Growing community of inventors

San Francisco, CA, United States of America

Jennifer Wang