Industrial Research Limited

Albert Einstein College of Medicine

Resene Paints Limited

Victoria Link Limited

Oncology Research International Limited

Callaghan Innovation Research Limited

Jennifer Mary Mason

Peter Charles Tyler

Gary Brian Evans

Vern L Schramm

Keith Clinch

Richard Hubert Furneaux

Peter Michael Kelly

Shivali Ashwin Gulab

Dirk Henning Lenz

Mark William Glenny

Colin Gooch

Simon Hinkley

Cameron Tristram

Dennis Williams

Richard Frohlich

Shivall Ashwah Ashwin Gulab

David Millar Walker

Andrew Clive Muscroft-Taylor

Richard Froehlich

Philip Andrew Marshall

Richard Fröhlich

The present invention relates to cellulose mixed esters, processes for preparing these and uses of the cellulose mixed esters, for example in coating compositions. The cellulose mixed esters have glass transition temperatures that fall within an appropriate range to allow for film formation to occur at ambient temperatures and have a total degree of substitution per anhydroglucose unit of about 2.5 to about 3.5; a residual hydroxyl functionality per anhydroglucose unit of 0 to about 0.5; a degree of substitution per anhydroglucose unit by C-Cester groups of about 0.5 to about 2.8; and a degree of substitution per anhydroglucose unit by Ievulinyl ester groups of about 0.2 to about 2.6.

Cellulose mixed esters

Inhibitors of saporin-L1 are disclosed, as are related compositions and uses thereof, in particular in cancer therapy that employs saporin-L1-linked immunotoxins.

Saporin-L1 inhibitors and uses thereof

The present invention relates to compounds of the general formula (I) which are inhibitors of 5'-methylthioadenosine phosphorylase or 5&#x2032;-methylthioadenosine nucleosidase. The invention also relates to the use of these compounds in the treatment of diseases or conditions in which it is desirable to inhibit 5&#x2032;-methylthioadenosine phosphorylase or 5&#x2032;-methylthioadenosine nucleosidase including cancer, and to pharmaceutical compositions containing the compounds.

Acyclic amine inhibitors of 5-methytioadenosine phosphorylase and nucleosidase

A process is disclosed for preparing (3R,4R)-3-hydroxy-4-hydroxymethylpyrrolidine, the compound of formula (I), or (3S,4S)-3-hydroxy-4-hydroxymethylpyrrolidine, the compound of formula (Ia) involving, as a key step, the enzyme-catalysed enantioselective hydrolysis of a racemic 3,4-trans-disubstituted pyrrolidinone compound of formula (II).

Method for preparing 3-hydroxy-4-hydroxymethyl-pyrrolidine compounds

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Petone, New Zealand

Jennifer Mary Mason