Covidien LP

Jennifer Makridakis

Gaurav Girdhar

Xiaodong Ma

An injectable non-aqueous composition and a method of treating a vascular disease, the non-aqueous composition including: chitosan having a particle size of no greater than 50 &#x3bc;m; alginate having a particle size of no greater than 50 &#x3bc;m; and a non-aqueous carrier; wherein upon combination and injection into the vascular system of a subject, the composition causes a diseased portion of the vascular system to be absorbed into surrounding tissue.

Injectable non-aqueous compositions and methods of treating vascular disease

Agents and methods are provided for breaking down and/or assisting in the removal of clots, in embodiments chronic clots, from the vasculature. In embodiments, the agents and methods may be used in the vasculature, in particular the peripheral venous vasculature, in order to prevent clot formation and/or lyse clots in patients suffering from complications, such as thrombosis, or from conditions, such as deep vein thrombosis (DVT).

Growing community of inventors

Mendon, MA, United States of America

Jennifer Makridakis