Medtronic Xomed, Inc.

Medtronic, Inc.

Jennifer Gates Medina

James B Hissong

Matthew Franco Myntti

Dana A Oliver

Jie Wen

Drew P Amery

Ethan Glenn Sherman

Brian J Vaccaro

Ethan Glenn Sherrman

Implants are placed in turbinate mucosal tissue using a surgical device having a proximal grip portion and a distal hollow sharp needle portion that is manipulated using the grip portion and inserted submucosally into mucosal turbinate tissue. One or more biodegradable, drug-eluting solid implants are disposed within the needle. The implants have one or more implant withdrawal-discouraging, mucosal tissue-engaging surface features along their length. An actuator disposed within the device is used to deliver one or more of the implants from the needle into the mucosal turbinate tissue and submucosally bury at least one such tissue-engaging feature therein.

Resorbable, drug-eluting submucosal turbinate implant device and method

Tissue and other body structures may be protected using a dry, free-flowing, sterilized mixture of chitosan particles and oxidized polysaccharide particles in sealed packaging. The mixture may assist in returning an injured, inflamed or surgically repaired surface to a normal state, e.g., through one or more healing mechanisms such as modulation of an inflammatory response, phagocytosis, mucosal remodeling, reciliation or other full or partial restoration of normal function.

Polysaccharide particle mixture

Body tissue and structures in an airway may be treated with an artificial scab comprising an inhomogeneous, uncohesive, solid sheet-like body comprising a granular mixture of chitosan and polysaccharide particles. The artificial scab breaks apart into smaller pieces if peeled away from the surgical site or wound, thus reducing the risk of airway occlusion.

Artificial scab for use in an airway

Chronic wounds may be treated by debriding necrotic and other devitalized tissue from the wound, and applying to the wound an extracellular polymeric substance solvating system comprising a metal ion sequestering agent, surfactant and buffering agent. The solvating system disrupts biofilms which may be present in the wound and aids or enables the resumption of normal healing.

Method for treating chronic wounds with an extracellular polymeric substance solvating system

A method for treating a wound with a ready-to-use composition having a high concentration of a water-soluble chitosan in a phosphate-containing solution. The composition is a paste at room temperature, has a pH of at least 4, adheres to the body tissue or surgical site and has a residence time of at least 1 day.

Chitosan paste wound dressing

Nasal or sinus site may be treated with a ready-to-use paste having a high concentration of a water-soluble chitosan, an osmolality reducing agent in a phosphate-containing solution. The paste forms at room temperature, has a pH of at least 4 and the osmolality reducing agent does not crosslink with the water-soluble chitosan. The paste provides stenting and adheres to the nasal or sinus site and has a residence time of at least 1 day.

Growing community of inventors

Jacksonville, FL, United States of America

Jennifer Gates Medina