Anacor Pharmaceuticals, Inc.

Avista Pharma Solutions, Inc.

Jennifer Freeman

Jacob J Plattner

Tsutomu Akama

Joe B Perales

Daitao Chen

Yvonne Freund

Eric Easom

Jessica Sligar

Jason Daniel Speake

Brent Christopher Beck

Bharathi Pandi

The present disclosure describes novel compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the disclosure have activity as prostaglandin EP4 receptor antagonists, and are useful in the treatment or alleviation of pain and inflammation and other inflammation-associated disorders, such as arthritis, treating or preventing disorders or medical conditions selected from pain, inflammatory diseases and the like. Also described herein are methods of treating pain by administering the compounds of the disclosure, which are EP4 receptor antagonists.

Chemical compounds

This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.

Boron-containing small molecules as antiprotozoal agents

Boron containing small molecules as antiprotozoal agents

This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent. 

Growing community of inventors

Durham, NC, United States of America

Jennifer Freeman