Boehringer Ingelheim International Gmbh

Bayer Healthcare LLC

Bayer Intellectual Property Gmbh

Jennifer Burke

Derek Cogan

Yunlong Zhang

Daniel Richard Marshall

John Lord

Michael Balestra

Xin Guo

Bryan Patrick McKibben

Jacques P Dumas

Barton W Phillips

Gan Wang

Wendy Lee

Zhidong Chen

Lee Fader

Maolin Yu

Kenneth Michael Meyers

Roger Astbury Smith

William Johnston Scott

Stephen J O'Connor

Kyle E Parcella

Tatiana Shelekhin

David Gunn

Roger John Snow

Thomas Martin Kirrane, Jr

Zhonghua Zhang

Keith R Hornberger

Mario Lobell

Yuanwei Chen

Jianmei Fan

Zhaoming Xiong

Peter Allen Nemoto

Ning Miao Su

Julie A Dixon

Zhi Chen

Stephen Boyer

Christiana I Iwuagwu

Aniko Redman

Qingming Zhu

Sharad Verma

Jianqing Chen

Jörg Martin Bentzien

Karl Miranda

Hui Yu

Lin Yi

Shihong Ying

Furahi Achebe

Stephen James Boyer

Andrea McClure

Jianxing Shao

Lila Adnane

Brian Raudenbush

Simon Suprenant

Kosea S Frederick

Frederick Ehrgott

Xin Ma

Derek Lowe

David Cantin

Matthew A Cerny

Bryan P Mckibben

Simon Surprenant

Thomas Martin Kirrane Jr

Jörg Bentzien

Kenneth M Meyers

Bryan Mckibben

The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein R, R, R, R, Rand n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes. 

Bicyclic imidazole derivatives useful for the treatment of renal diseases, cardiovascular diseases and fibrotic diseases

The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein X, R, Rand Rare as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes. 

Aldosterone synthase inhibitors

The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein Cy, Rand Rare as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R, R, R, R, R, R, R, W, Y, m and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

The present invention relates to compounds of Formula (I) and pharmaceutically acceptable salt thereof, wherein R, R, R, R, Rand n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes. 

Heterocyclic compounds containing a pyrrolopyridine or benzimidazole core

This invention relates to novel compounds of formula (I). Formula (I) in which the variable groups are as defined in the specification and claims, to pharmaceutical compositions containing them, and to a method of treatment using them for treatment of cancer. 

Pyrrolo[2,1-f][1,2,4]triazin-4-ylamines IGF-1R kinase inhibitors for the treatment of cancer and other hyperproliferative diseases

This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.

Bicyclic urea derivatives useful in the treatment of cancer and other disorders

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Newtown, CT, United States of America

Jennifer Burke