Harvard College

University of Illinois

Lawrence Livermore National Security, LLC

Massachusetts Institute of Technology

Northwestern University

Massachusetts Eye and Ear Infirmary

Universiteit Twente

Eth Zurich (swiss Federal Institute of Technology)

Sandia Corporation

W.r. Grace & Co. -conn.

The Brigham and Women's Hospital, Inc.

Karlsruher Institut Fur Technologie

Jennifer Ann Lewis

David B Kolesky

Mark Andrew Skylar-Scott

Kimberly A Homan

Eric B Duoss

John J Vericella

Christopher M Spadaccini

Roger D Aines

William L Bourcier

Joshuah K Stolaroff

Jochen Mueller

Scott R White

Joseph Thomas Muth

Theodore H Fedynyshyn

Travis Alexander Busbee

Daniele Foresti

Mark C Hersam

Robert J Wood

Michael J McKenna

Kanan P Puntambekar

Ethan B Secor

Michael L Geier

Yu Teng Liang

Pradyumna L Prabhumirashi

Bradley P Duncan

John Rosowski

Claas Willem Visser

Aaron K Remenschneider

Daniel J Lee

Daniel M Vogt

Yigit Menguc

George M Church

Ralph G Nuzzo

Jeffrey S Moore

Nancy R Sottos

Sarah Elyse Baker

Kevin Kit Parker

Christopher M Hansen

Ara A Jeknavorian

Ranjeet Balakrishna Rao

Duane B Dimos

Jeffery James Roberts

Josephine Ho-Wah Cheung

William C Floyd, Iii

Elaine Lee

Joseph Cesarano, Iii

Patrick Lustenberger

Joost Johan Vlassak

Norbert Willenbacher

Ryan L Truby

Jordan R Raney

Thomas J Ober

Daniel Therriault

Gregory Gratson

Nicole Black

Armand Kurum

Kristina Shea

Alexander D Valentine

Dahlia Ningrum Amato

Bok Y Ahn

Katharina Theresa Kroll

Krystyn J Van Vliet

Johan Ulrik Lind

Amitesh Maiti

Elliott Kozin

Michael Austin Bell

Qi Li

Kathleen S Toohey

Sebastien G M Uzel

Caitlyn Christian Krikorian

Anna Jagielska

Robert F Shepherd

Robert A Barry, Iii

Sara T Parker

Jennifer N H Shepherd

Alex H M Ng

Pierre Wiltzius

Mariusz Twardowski

Bok Yeop Ahn

Elliot Kozin

Glen Kirby

Yen-Chih Lin

Sherry L Morisette

Rodrigo Telles Arriaga

Ian Perkins

Aleksandra Markovic

Maxwell E Plaut

Christophe Chantre

Teng-Sing Wei

John E Minardi, Ii

Hongyan Yuan

Natalie M Larson

Amelia Sydney Gladman

Sebastien Uzel

James O Hardin, Iv

Michael T Lis

Steven Kranz

A method of 3D printing a battery includes extruding a first electrode ink formulation through a first deposition nozzle moving relative to a substrate, and depositing one or more continuous filaments comprising the first electrode ink formulation on the substrate to print a first electrode. A separator ink formulation is extruded through a second deposition nozzle moving relative to the substrate, and one or more continuous filaments comprising the separator ink formulation is deposited on the first electrode to print a separator precursor, which is then cured to form a separator. A second electrode ink formulation is extruded through a third deposition nozzle moving relative to the substrate, and one or more continuous filaments comprising the second electrode ink formulation is deposited to print a second electrode on the separator. The first and second electrodes and the separator are enclosed in a package, thereby forming a battery with thick electrodes.

3D printed battery and method of 3D printing a battery

Described are methods for producing tissue constructs, tissue constructs produced by the methods, and their use. The described method of producing a tissue construct comprises providing a granular tissue, depositing one or more filaments on or in the granular tissue, each filament comprising an ink, and gelling or fusing the granular tissue, thereby producing the tissue construct.

Tissue construct, methods of producing and using the same

Described are methods of enhancing development of renal organoids, methods of using the same, and kits.

Methods of enhancing development of renal organoids and methods of using the same

Described are methods for producing multi-layered tubular tissue structures, tissue structures produced by the methods, and their use.

Methods of producing multi-layered tubular tissue constructs

A method of printing a cellular solid by direct bubble writing comprises introducing an ink formulation comprising a polymerizable monomer and a gas into a nozzle, which includes a core flow channel radially surrounded by an outer flow channel. The ink formulation is directed into the outer flow channel and the gas is directed into the core flow channel. The ink formulation and the gas are ejected out of the nozzle as a stream of bubbles, where each bubble includes a core comprising the gas and a liquid shell overlying the core that comprises the ink formulation. After ejection, the polymerizable monomer is polymerized to form a solid polymeric shell from the liquid shell, and the bubbles are deposited on a substrate moving relative to the nozzle. Thus, a polymeric cellular solid having a predetermined geometry is printed.

Method of 3D printing a cellular solid

A method of acoustophoretic printing comprises generating an acoustic field at a first end of an acoustic chamber fully or partially enclosed by sound-reflecting walls. The acoustic field interacts with the sound-reflecting walls and travels through the acoustic chamber. The acoustic field is enhanced in a chamber outlet at a second end of the acoustic chamber. An ink is delivered into a nozzle positioned within the acoustic chamber. The nozzle has a nozzle opening projecting into the chamber outlet. The ink travels through the nozzle and is exposed to the enhanced acoustic field at the nozzle opening, and a predetermined volume of the ink is ejected from the nozzle opening and out of the acoustic chamber.

Apparatus and method for acoustophoretic printing

A printhead comprises a plurality of ink cartridges and a nozzle, where the nozzle and the ink cartridges are configured to rotate together about an axis during printing. The nozzle includes a nozzle body comprising an inlet end, an outlet end, and one or more internal passageways extending through the nozzle body from the inlet end to the outlet end. The one or more internal passageways terminate at one or more outlets at or near the outlet end. The nozzle also includes plurality of nozzle inlets at the inlet end for delivery of flowable inks into the internal passageways, where each nozzle inlet is in fluid communication with a dispensing end of one of the ink cartridges.

Printhead and method of printing multimaterial filaments including oriented, twisted and/or helical features

In one aspect, the present disclosure provides a nozzle for aD printing system. The nozzle may include a flowpath with a material inlet and a material outlet. The nozzle may further include a valve in fluid communication with the flowpath between the material inlet and the material outlet, where the valve includes a closed state and an open state, where in the closed state the valve obstructs the flowpath between the material inlet and the material outlet, and where in the open state the material inlet is in fluid communication with the material outlet. The nozzle may further include a compensator in fluid communication with the flowpath, where the compensator includes a contracted state associated with the open state of the valve and an expanded state associated with the closed state of the valve.

Valved nozzle with a compensator and massively parallel 3D printing system

A subwavelength resonator for acoustophoretic printing comprises a hollow resonator body for local enhancement of an acoustic field integrated with a nozzle body for delivery of an ink into the acoustic field. The nozzle body has a first end outside the hollow resonator body and a second end inside the hollow resonator body, and includes a fluid channel extending between a fluid inlet at the first end and a fluid outlet at the second end. The fluid channel passes through a side wall of the hollow resonator body and includes at least one bend. During acoustophoretic printing, an ink delivered through the fluid channel of the nozzle body and out of the fluid outlet is exposed to a high-intensity acoustic field.

Subwavelength resonator for acoustophoretic printing

A 3-D printed device comprising one or more structures, the structures comprising a plurality of magnetically responsive particles and one or more diblock or triblock copolymers; the diblock or triblock copolymers having an A-B, A-B-A, or A-B-C block-type structure in which the A-blocks and C-blocks are an aromatic-based polymer or an acrylate-based polymer and the B-blocks are an aliphatic-based polymer. These 3-D printed devices may be formed using a method that comprises providing a magnetic ink composition; applying the magnetic ink composition to a substrate in a 3-D solvent cast printing process to form one or more structures; and drying the one or more structures formed from the magnetic ink composition. The dried structures can exhibit one or more regions of magnetic permeability greater than 1.3×10H/m.

3-d printed devices formed with magnetic inks and methods of making graded index structures

A method of forming a three-dimensional structure includes forming a layer of resin comprising liquid crystal oligomers and a photoinitiator, applying a magnetic field to the formed layer in a predefined alignment direction for substantially aligning the liquid crystal oligomers in a first orientation; and exposing the formed layer to radiation for curing a first portion of the layer during application of the magnetic field thereby resulting in the first portion having liquid crystal elastomers substantially aligned in the first orientation. The method includes applying a second magnetic field to the formed layer in a predefined second alignment direction for substantially aligning uncured liquid crystal oligomers in a second orientation, and exposing the layer to radiation for curing a second portion of the layer during application of the second magnetic field thereby resulting in the second portion having liquid crystal elastomers substantially aligned in the second orientation.

Stereolithography additive manufacturing of magnetically aligned liquid crystal elastomers

A method of printing a cellular solid () by direct bubble writing comprises introducing an ink formulation () comprising a polymerizable monomer and a gas () into a nozzle (), which includes a core flow channel () radially surrounded by an outer flow channel (). The ink formulation is directed into the outer flow channel () and the gas is directed into the core flow channel (). The ink formulation () and the gas () are ejected out of the nozzle () as a stream of bubbles (), where each bubble includes a core () comprising the gas and a liquid shell () overlying the core that comprises the ink formulation. After ejection, the polymerizable monomer is polymerized to form a solid polymeric shell () from the liquid shell (), and the bubbles are deposited on a substrate () moving relative to the nozzle (). Thus, a polymeric cellular solid () having a predetermined geometry is printed.

This disclosure features artificial tympanic membrane graft devices and two-component bilayer graft devices that include a scaffold having a plurality of ribs made of a first material and a plurality of spaces between the ribs filled or made with the first material, a different, second material, a combination of the first and a second materials, or a combination of a second material and one or more other different materials. The bilayer graft devices have two components or layers. One component, e.g., the underlay graft device, can include a projection, and the second component, e.g., the overlay graft device, can include an opening that corresponds to the projection (or vice versa) so that the opening and the projection can secure the two layers together in a 'lock and key' manner. This disclosure also features methods of making, using, and implanting the three-dimensional artificial tympanic membrane and bilayer graft devices.

Artificial tympanic membrane devices and uses

Described are devices and methods for use in connection with organ replacement or organ assist therapy in a patient.

Living devices for replacement of organs or specific organ functions, methods and uses of the same

Growing community of inventors

Cambridge, MA, United States of America

Jennifer Ann Lewis