Spiration, Inc.

Jenni Rimbaugh

Lauri J DeVore

Clifton A Alferness

Hugo Xavier Gonzalez

David H Dillard

Dean T Corcoran

Seung Yi

Mia Park

Robert Lawrence Barry

Clint Finger

Leslie Snyder

An intra-bronchial device placed and anchored in an air passageway of a patient to collapse a lung portion associated with the air passageway. The device includes a support structure, an obstructing member carried by the support structure that reduces ventilation to the lung portion by preventing air from being inhaled into the lung portion, and at least one anchor carried by the support structure that anchors the obstruction device within the air passageway. The anchor may engage the air passageway wall by piercing or friction, include a stop dimensioned for limiting the piercing of the air passageway wall, and may be releasable from the air passageway for removal of the intra-bronchial device. The anchors may be carried by a peripheral portion of the support structure, or by a central portion of the support structure. The obstructing member may be a one-way valve.

One-way valve devices for anchored implantation in a lung

An apparatus and method deploy a self-expandable bronchial obstruction device in an air passageway. The apparatus includes a catheter configured to be passed down the trachea. The apparatus further includes a capsule for housing the self-expandable bronchial obstruction device in a sterile environment. The capsule is configured to be advanced down the catheter. The capsule further includes a tubular extension. The capsule has a breakable seam so as to release the bronchial obstruction device in the air passageway upon a proximal force being exerted upon the bronchial obstruction device. The method includes guiding a conduit down a trachea into the air passageway. The method further includes advancing a capsule having a bronchial device therein down an internal lumen of the conduit into the air passageway. The method further includes releasing the bronchial device from the capsule. The method further includes deploying the bronchial device into the air passageway.

Apparatus and method for deployment of a bronchial obstruction device

Methods of achieving lung volume reduction with removable anchored devices

A method of reducing the size of a lung by collapsing a target section of the lung includes delivering within a lung air passageway leading to the target section an intra-bronchial device. The device is deployed in a desired location and then the device is removed from the desired location. The device can be removed by gripping a portion of the device with a retractor device, which is used to draw the device proximally. Proximal movement releases anchors of the device from the passageway and the anchors can be collapsed into a removal configuration.

A constriction device that constricts body tissue includes fixation structures for fixing the device on constricted body tissue. The device includes an elongated sleeve including an inner surface and opposed opened ends. The device is formed from expandable or elastic material so that when in an expanded condition, body tissue to be constricted may be received therein and thereafter, when released from the expanded condition, the body tissue is constricted by the device. The fixation structures include a plurality of fixation elements on the inner surface of the sleeve that grasp the body tissue upon release of the sleeve from the expanded condition to fix the device on the constricted tissue.

Constriction device including fixation structure

A system and method deploys a bronchial obstruction device in an air passageway communicating with a lung portion to be at least temporarily collapsed. The system includes a conduit configured to be passed down a trachea, into a bronchus communicating with the trachea and into the air passageway communicating with the lung portion. The system further includes a capsule dimensioned to house the bronchial obstruction device and to be advanced down an internal lumen of the conduit into the air passageway. The capsule has a break-away distal end configured to release the bronchial obstruction device for deployment in the air passageway upon being pushed from the capsule by a pusher member.

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Bothell, WA, United States of America

Jenni Rimbaugh