University of California

Leading Biosciences, Inc.

Inflammagen, LLC

Other

Industrial Technology Research Institute

Jeng Wei

Geert W Schmid-Schonbein

Yung-Tsai (Andrew) Lee

Jui-Hsiang Chen

Andrew Teh Hu

Geert W Schmid-Schoenbein

Muh-Lan Chen

Yu-Der Lee

Chung-Yi Chang

Shu-Fang Jiang

Ru-Fong Laiw

Andrew Lee

Fan-Yen Lee

A blood conduit with stent has a flexible conduit body and an expandable stent structure. The conduit body has a first opening end through which only an inflow of a blood enters and a second opening end through which only an outflow of the blood leaves. The stent structure includes a plurality of threads adhered to the conduit body and expands in directions intersecting an axial direction of the conduit body. A boundary of one of the threads of the stent structure closest to the second opening end is away from the second opening end with a predetermined distance, thereby preventing blood back flow into the false lumen via a new tear.

Blood conduit with stent

The inventors have unexpectedly discovered that shock and/or potential multi-organ failure due to shock can be effectively treated by administration of liquid high-dose protease inhibitor formulations to a location upstream of where pancreatic proteases are introduced into the gastrointestinal tract. Most preferably, administration is directly to the stomach, for example, via nasogastric tube under a protocol effective to treat shock by such administration without the need of providing significant quantities of the protease inhibitor to the jejunum and/or ileum.

Administration of serine protease inhibitors to the stomach

A porous polyurethane tube suitable for use as a vascular graft prosthesis is prepared by placing solvent type polyurethane resin coated mandrel in a static coagulant consisting of water, ethanol and optionally aprotic solvent within 30 seconds immediately after the coating step, separating the tube by placing the mandrel in a swelling agent containing at least 90 percent by weight of ethanol and rinsing with a solution containing at least 80 percent by weight ethanol.

Method for preparing a porous polyurethane vascular graft prosthesis

Growing community of inventors

Taipei, Taiwan

Jeng Wei