Medical and Pharmaceutical Industry Technology and Development Center

Oneness Biotech Co.

Jen-Wei Chen

Feng-Nien Ko

Mo-Chi Cheng

Cheng-Ko Liu

Fen Chen

Chao-Chi Yei

Kung-Ming Lu

Wen-Ling Yang

The invention provides an extract of(Lour.) Spreng enriching anti-arthritis activity, which is obtained by eluting the crude extract of(Lour.) Spreng using 50%&#x2dc;95% alcoholic solution or solvents such as hexane and/or ethyl acetate. Also provided is a method for treating arthritis comprising such extract.

Method for preparingfraction having anti-arthritis activity

The present invention provides a topical formulation comprising an active agent, which comprises salvigenin and optionally asiaticoside. The present invention also relates to the use of the topical formulation for the promotion of wound healing.

Topical formulation for promoting wound healing

A new use of a potent product extracted from rhizomes ofin treating a disease associated withsuch as gastritis, gastric ulcer or duodenal ulcer in a patient. The potent product is prepared by a process including the steps of a) preparing a crude extract from rhizomes of, said crude extract comprising 6-gingerol and 6-shogaol; b) introducing the crude extract to a normal phase chromatography column, and eluting the column with a first eluent having a polarity lower than that of a mixture of n-hexane and ethyl acetate in a weight ratio of 6:4 to obtain a potent fraction. Preferably, the potent fraction is substantially free of both 6-gingerol and 6-shogaol.

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The present invention discloses a new use of a potent product extracted from rhizomes ofin treating a disease associated withsuch as gastritis, gastric ulcer or duodenal ulcer in a patient. The potent product is prepared by a process including the steps of a) preparing a crude extract from rhizomes of, said crude extract comprising 6-gingerol and 6-shogaol; b) introducing the crude extract to a reverse phase chromatography column, and eluting the column with a first eluent having a polarity lower than water to obtain a first potent fraction or a second eluent having a polarity lower than that of the first eluent to obtain a second potent fraction. Preferably, the second potent fraction is substantially free of both 6-gingerol and 6-shogaol.

Growing community of inventors

Taipei, Taiwan

Jen-Wei Chen