University of Michigan

Flipsi Ltd.

University of California

Dow Silicones Corporation

Jeffrey Stephen Plott

Albert J Shih

Christopher J Plott

Yang Liu

Paul S Cederna

Yihao Zheng

Luis Emilio Savastano

Albert Jau-Min Shih

Kevin R Ward

Grant H Kruger

Cynthia Anne Chestek

Jordan T Kreda

Bizhong Zhu

Herschel Henry Reese

Melanie G Urbanchek

David A Zopf

Kevin Tremper

Nicholas B Langhals

Lance S Patak

Matthew Hildner

Sanghamithra Kalimi

Jahnavi Nalamolu

Gene Philip Parunak

Chun Hei So

Nisha Bharat

Jeffrey H Kozlow

Yvonne Wu

Shriya Suresh

Katie Munson

Celia Clark

Dian-Ru Li

Nishant Ganesh Kumar

Allison Powell

Hongjun Wang

Kirsten Boelkins

Jonathan William Zwier

Krishna Mahajan

Kelsey L Luibrand

Martin Sisolak

Sebastian Kwon

Aaron S Farberg

Adeyiza Momoh

Thuan Doan

Joel L Kileny

Daniel Edward Lee

Xiaoqing Tian

Stanley Yee

Gardner Yost

Alon Kahana

David Adam Zopf

The present disclosure provides a mechanically-actuated tool for cutting a tissue graft having a hollow core and methods for use thereof. A portion of a biological structure, such as a nerve, is attached to the hollow core to form an implantable neural graft assembly. The tool has a cutter mechanism and a grasper mechanism. The grasper mechanism has one or more component(s) that open and close via an actuation mechanism, like a handle, and rotate via a controller component, like a rotatable wheel. The cutter mechanism may be a cutting tube component that harvests the tissue graft. The tool may also have an ejector mechanism to remove the tissue graft as part of the implantable neural graft assembly. Such devices and methods are particularly suitable for treating neuromas and other neural regeneration procedures.

Tool for neuroma treatment and nerve regeneration procedures

A junctional hemorrhage control device includes a strap and a base operably connected to the strap. A strap carriage is operably connected to, and linearly translatable relative to, the base. A screw assembly is rotatably attached to the base. The screw assembly moves the strap carriage away from the base when the screw assembly is operated in one direction and towards the base when the screw assembly is operated in an opposite direction. A removable pressure plate is attached to the base to apply occlusion pressure to a hemorrhage location.

Junctional hemorrhage occlusion device

An actuated telescoping system for navigation within a vascular lumen and thrombectomy of a thrombus. The system includes a tubular catheter member having an open distal end defining a catheter lumen, a vacuum source, a rotational drive system, a flexible shaft having a channel coupled to the rotational drive system for rotational movement in response thereto, and an optional guidewire selectively inserted at least partially within the flexible shaft. The flexible shaft is at least partially disposed within the tubular catheter member configured for uncoupled rotational and translational motion therein and to optionally define a corkscrew motion in response to rotational driving force by the drive system that results in formation of hydrodynamic vortices within the catheter lumen. The telescoping system can be capable of reversibly transitioning between navigation and thrombectomy modes by differentially disposing and actuating the components and enable faster, more efficient and simpler removal of thromboembolic material.

Hydrodynamic vortex aspiration catheter

An example nasal airway tube includes a tubular body having a distal end and a proximal end. A surface at the distal end including an opening. The tubular body having an overall curvature with a radius of curvature defined relative to a longitudinal axis of the tube. An X-axis is defined by the longitudinal axis of the tube, and a Y-axis extends perpendicularly from the longitudinal axis and has a positive direction defined outwardly relative to the radius of curvature. At least a portion of the opening faces outwardly relative to the radius of curvature. A vector normal to a plane defined by the opening includes a positive Y-coordinate.

Nasal airway device and kit

A device for wound irrigation and debridement includes a body extending along a longitudinal axis. The body comprises an interior region and an opening such that that the interior region and the first opening are configured to transfer an irrigation fluid. The body comprises a compliant region having a first stiffness and a debridement region having a different second stiffness. The compliant region defines a distal surface. In a first configuration, the compliant region defines a first axial dimension, the distal surface engages a target body region, and the debridement region is axially offset from the distal surface and disengaged from the target body region. In a second configuration, the compliant region is compressed to define a second axial dimension less than the first axial dimension, thereby engaging the debridement region with the target body region, and the distal surface engages the target body region.

Device and method for wound irrigation and debridement

An anti-hemorrhage device, and an anti-hemorrhage kit, includes a rigid platform and a compression device adjustably secured to the rigid platform. The kit also includes a gastroesophageal aortic occlusion device.

Anti-hemorrhage device with rigid back plate

A device for detecting postpartum hemorrhage is provided. A mat defines a proximal end and a distal end. The mat is configured to be disposed between a support and a patient and has a surface with a fluid flow region configured to direct flow of bodily fluids from the patient towards the distal end of the mat. A first detachable and optionally sealable bag is configured to receive the bodily fluids from the patient in a first operational mode of the device. A second sealable bag is configured to receive the bodily fluids from the patient in a second operational mode of the device. The second sealable bag comprises a visual volume indicator to measure the bodily fluids collected in the second sealable bag.

Device for blood loss measurement following childbirth to detect postpartum hemorrhage

A method of forming a porous three-dimensional (3D) is disclosed. The method comprises (I) printing a first composition on a substrate () with the nozzle () of the apparatus () to form at least one first filament () comprising the first composition, (II) selectively controlling the distance and/or the speed such that the at least one first filament coils on the substrate to give a first layer on the substrate, the first layer comprising a coiled filament, optionally repeating steps I) and II) with independently selected composition(s) for any additional layer(s), and (III) exposing the layer(s) to a solidification condition. A porous three-dimensional (3D) article formed in accordance with the method is also disclosed.

Method of forming porous three-dimensional (3D) article

An everter device to facilitate preparation of ends of arterial segments for end-to-end microvascular anastomosis. The device includes structure that provides sufficient support to prevent unwanted buckling of arterial tissue. The everter device offsets the tendency of the arterial tissue wall to recover its natural shape and fall off securement posts or pins of a coupler ring. The structure may be in the form of an intraluminal catheter balloon. Alternately, the structure may be in the form of a plunger. Alternately, the structure may be in the form of a radially expanding member provided on a shaft. The device further has a contoured surface on an everter end to evert a free end of arterial tissue over a coupler ring, and to cause the posts or pins of the coupler ring to pierce through the everted arterial tissue. The everter end is provided with one or more openings therein, such as a circumferential slot, to receive the posts or pins of the coupler ring.

Device to aid in arterial microvascular anastomosis

Beverage container insert

A portable compact tourniquet includes a pivot housing, a strap carriage that is linearly translatable relative to the pivot housing, and a screw assembly. When the screw assembly is operated, the strap carriage away from the pivot housing, thus tightening a tourniquet strap that is attached to the strap carriage and to the pivot housing.

Tourniquet

Growing community of inventors

Algonac, MI, United States of America

Jeffrey Stephen Plott