Other

Exelixis, Inc.

Synthes Spine Company, LP

Raytheon Company

Sun Microsystems, Inc.

Ocado Innovation Limited

Iterion Therapeutics, Inc.

Tvardi Therapeutics, Inc.

Jeffrey Scott Larson

Stephen Horrigan

Lori Friedman

Theodore P Bertele

Louis E Greenberg

Theodore Laslo

Steven David Dykstra

Henry Havel

Scott Schorer

Jonathan Northrup

Gregory D Plowman

Andrew B Facciano

Srinivas Rao Kasibhatla

Garry Thomas Gwozdz

Helen Louise Francis-Lang

Marcia Belvin

Noah Mcneely

Darren Platt

Jerry Vance Foster, Iii

Sofia De Achaval

Michael S Alkema

Andrew Roy Buchman

Kevin Patrick Keegan

Imran Alibhai

Casey Kopczynski

Michael A Barker

Catherine Jones Franey

Roger D Harrison

Jonathan Schweiger

Stephanie A Robertson

Steven Brian Gendreau

Emery G Dora, Iii

Gary Cole

Michael Martin Ollman

Madelyn Robin Demsky

Danielle L W Barringer

David M W Hemming

Michael A Costa

Roger Harrison

William G Graves

Brad Henke

Garry Gwozdz

Ruolan Han

Monique Nicoll

Jon Northrup

Lenore Urbani

Lynn Marie Young

Disclosed are systems and methods for dynamically routing pickers and autonomous vehicles to avoid areas closed to travel by the autonomous vehicles within a warehouse. A processor in communication with an autonomous vehicle and an electronic device operated by a user (e.g., handheld device) may, in response to detecting that the electronic device diverges from a path of the autonomous vehicle, provide, for display on the electronic device, information about the product. The processor may then determine a rendezvous location for the autonomous vehicle based on a location of the product. The processor may then instruct the autonomous vehicle to navigate to the rendezvous location and transmit the rendezvous location to the electronic device.

Dynamic routing of autonomous vehicles

A game system according to various embodiments of the subject disclosure may include a game piece and a game piece manipulator configured to hold the game piece. The game piece manipulator may include a first surface comprising a first electrically conductive portion and a controller configured to control an electric stimulus emitted by the game piece manipulator. The game piece manipulator may emit the electric stimulus by the first electrically conductive portion. The game piece may further include a power supply.

Electrified game piece manipulation game and game piece manipulator

Formulations of tegavivint and related compounds, methods of making such formulations and methods of treating various conditions utilizing such formulations.

Formulations of tegavivint and related compounds

Provided herein, in certain embodiments, are compounds of Formula I. or a pharmaceutically acceptable salt or a solvate thereof, compositions comprising a compounds of Formula I, or a pharmaceutically acceptable salt or a solvate thereof, and uses thereof such as in treating certain diseases or disorders (e.g., cancer, fibrosis, chronic inflammation).

Prodrugs of STAT3 inhibitors

A wine funnel for facilitating the transfer of wine from a bottle to a decanter includes a frustoconical housing having a top wall, a substantially continuous outer wall, and a lower end. Centrally positioned on the top wall is an elevated ball for dispersing wine into smaller, multidirectional streams. The top wall also includes a plurality of concentric grooves that trap sediment from wine deflected by the ball. The grooves are in fluid communication with an internal spiraled passageway having a plurality of venturi ports for efficiently importing ambient air into wine as it flows through the housing and into a decanter or wine glass.

Wine funnel

A game system includes a base having a top base surface and a controller, and a game piece manipulator including a surface having an electrically conductive portion. The game piece manipulator is configured to hold a game piece. The top base surface is configured to receive a plurality of game pieces. The controller is configured to control an electric stimulus emitted by the game piece manipulator, and the game piece manipulator is configured to emit the electric stimulus by the electrically conductive portion. A game piece manipulator includes at least one electrically conductive portion positioned on a surface of the game piece manipulator and is configured to connect to a base and receive control signals by a controller of the base and emit an electric stimulus. A game kit includes a base, a game piece manipulator, and a plurality of game pieces.

Methods for treatment of fibrotic diseases using compounds of formula I 

Methods for treatment of fibrotic diseases

A filling device may be used to fill a ball or other inflatable item from a water source such as a hose. A filling device may include an adapter having a cylindrical body with a hollow threaded interior, one closed end and one open end. A filling coupler is coupled to the one closed end of the cylindrical body. The one closed end of the cylindrical body has an opening formed therethrough and the filling coupler is coupled to the one closed end covering the opening. The filling coupler has a hollow threaded interior in fluid communication with the opening. A tip may be removably coupled to the filling coupler. The tip may be a ball inflation needle, a water balloon filling tip or the like.

Illuminated ball

An illuminated ball may be used to play games in the water. An illuminated ball may include a hollow, spherical shell. A translucent light housing may be coupled to the shell. A light emitting device may be within the translucent housing. A battery housing coupled to the light emitting device. At least one battery may be within the battery housing. A circuit board may be coupled to the battery housing. Four conductors may be coupled to the circuit board, wherein two of the four conductors are coupled to the light emitting device and another two of the four conductors are coupled to at least two water contacts. The at least two water contacts are located on an outside of the illuminated ball, wherein on exposure to water, the at least two water contacts are electrically connected causing the light emitting device to emit light.

A wine-glass polisher includes a housing having at least one cleaning chamber defined by a bottom wall and at least one sidewall. Extending from the sidewall is a wine-glass holder including a horizontal arm having a C-shaped gripping member at a distal end for holding the stem of an inverted wine glass. Immediately above the gripping member is a motorized disc for engaging the base of a wine glass to rotate it during a cleaning and drying cycle. Mounted on the sidewall, below the wine-glass holder, is an upper dispensing nozzle for projecting either drying air or steam onto the exterior surface of a wine glass. Upwardly extending from the bottom wall of the cleaning chamber is a lower dispensing nozzle for projecting drying air or hot water onto the interior surface of a wine glass. Hot water and air are sequentially delivered to the nozzles to clean and subsequently dry a wine glass.

Wine glass polisher

A flight vehicle includes a nose portion, a fuselage retaining structure aft of the nose portion, and an axial motor for expelling axial thrust along a longitudinal axis of the flight vehicle. Radial motors are coupled to the retaining structure and axisymmetrically arranged about the axial motor. Each radial motor is configured to expel radial thrust radially outwardly in respect to the flight vehicle. Roll thrusters are operatively coupled with the radial motors and coupled to the fuselage retaining structure. The roll thrusters are configured to provide a roll moment of the flight vehicle about a central longitudinal axis of the flight vehicle. Ejectors are operatively coupled to the radial motors, and a controller is operatively coupled to the radial motors and the ejectors. The controller is configured to selectively fire and selectively eject the radial motors to maintain relative centering of a center of gravity of the flight vehicle.

Rocket cluster divert and attitude control system

A cover assembly for use to protect the contents of a boat including a pair of channels, a semi-rigid guide member slidably disposed within a passage of one of the channels, a crossrod supported on each end by one of the pair of channels and connected on one end to the semi-rigid guide member, and a cover sheet connected to the crossrod. The cover assembly configured such that as a retraction mechanism moves the semi-rigid guide member in the passage, the cover is extended or retracted to the desired position.

Retractable boat cover assembly

A wine-glass polisher includes a base unit having a frustoconical cleaning chamber removably fastened thereto. A steam generator, an air heater and a vacuum pump are each in fluid communication with the cleaning chamber. A portion of the steam and hot air is directed to a channel formed in the chamber outer wall. An annular, U-shaped baffle surrounding the open top is in fluid communication with the channel for projecting the steam and hot air downwardly toward a wine glass below. A remaining portion of the heated air and steam is delivered directly to the upper surface of the base unit to clean and dry the interior surface of the glass. A controller first initiates a polishing cycle by activating the vacuum pump and steam generator. Upon expiration of the predetermined duration, the controller activates the blower to dry the exterior and interior surfaces of the glass.

Human TAOJIK genes are identified as modulators of the beta-catenin pathway, and thus are therapeutic targets for disorders associated with defective beta-catenin function. Methods for identifying modulators of beta-catenin, comprising screening for agents that modulate the activity of TAOJIK are provided.

TAOJIKs as modifiers of the beta-catenin pathway and methods of use

Growing community of inventors

Idaho Falls, ID, United States of America

Jeffrey Scott Larson