Foundation Medicine, Inc.

Other

Armstrong World Industries, Inc.

Awi Licensing Company

Syfr, Inc.

Afi Licensing LLC

The Azek Group LLC

Wisconsin Alumni Research Foundation

Cpg International LLC

Millenium Pharmaceuticals, Inc.

Cequint, Inc.

Kibur Medical, Inc.

Earth First Air Systems, Inc.

Ninepoint Medical, Inc.

Jeffrey S Ross

Dong Tian

Philip James Stephens

Doron Lipson

Gary A Sigel

Shazi S Iqbal

Vincent A Miller

Rebecca L Winey

Fang Qiao

Matthew J Hawryluk

Siraj Mahamed Ali

Ronald G Chang

Douglas Bryan Dority

Roman Yelensky

Steven M Montgomery

Garrett Michael Frampton

Gregory Edward Mote

Larry W Leininger

Bruce Edward Stanhope

Gary Palmer

Jie He

Maureen T Cronin

Merrill S Ross, Ii

Shahin Iqbal

Shiraz Iqbal

Jerome D Wisnosky

Robert D Hensel

David Joel Parker, Jr

Peter Warburton

Daniel Wesley Davies

Robert A Hallman

Christopher J Flaherty

Jason E Fuller

J Christopher Flaherty

Mark Gosselin

Ronald S Lenox

James Stephanick

Robert I Tepper

Leonard N Ray, Jr

Jason Fuller

Richard E Herr, Jr

Bennett E Wallick

Eugene M Kirchner

Elizabeth A Malkowski

Joseph F Reuwer, Jr

Craig Muir

Cesar Samano

Jessica L Duda

Russell Hirsch

Bradley J Ross

Carl J Ross

Timothy Wandell

Mary Kate Boggiano

Mark H Gosselin

Ronald Albert Hume

Tian Dong

Susan Monroe

Courtney R Price

Methods and compositions for treating cholangiocarcinoma.

Methods of treating cholangiocarcinoma

Novel mutant ESR1 molecules and uses are disclosed.

Estrogen receptor mutations and uses thereof

Aspects described herein are directed to compositions, systems, and methods of manufacturing a polymer-based construction material comprising polymeric resin and filler such as calcium carbonate (CaCO). A surface of the polymer-based construction material may be treated such that the surface energy is increased from the material's inherent value to a predetermined value of at least 40 dynes/cm. Further, the surface energy of the treated surface may persist within 20% of the predetermined value for at least three days.

Polymer-based construction materials

Polymer-based sheet materials having a variegated appearance are provided. The polymer-based-sheet material may have a core with one or more caps. The cap(s) may be on a first primary surface, a second primary surface, and/or sides. The variegation may be within and/or on the cap and/or the core. Methods, systems, articles, and materials effective for a polymer-based sheet material having a variegated appearance are provided.

Variegated polymer-based materials

Aspects described herein are directed to compositions, systems, and methods of manufacturing a polymer-based construction material comprising polymeric resin, filler such as calcium carbonate (CaCO), and titanium oxide (TiO). A surface of the polymer-based construction material may be treated such that the surface energy is increased from the material's inherent value to a predetermined value of at least 40 dynes/cm. Further, the surface energy of the treated surface may persist within 20% of the predetermined value for at least three days.

An abrasion resistant flooring covering formed from a UV curable coating composition having binder and diamond particles&#x2014;the abrasion resistant flooring covering used to overcoat the surface of flooring products or various abrasion heavy surfaces to protect such a products or surfaces from damage by abrasion or scratch.

Scratch resistant coating

A user may move a specimen holder from one specimen rack to another specimen rack. A database automatically tracks the movement of the specimen holder from a rack slot of one specimen rack to a rack slot of the other specimen rack. To track movement of the specimen holder, the user places a specimen rack on a specimen reader that determines the location of any specimen holders in slots of the specimen rack. The user removes a particular specimen holder from a particular rack slot of the specimen rack and the database is updated to reflect removal of the particular specimen holder from the specimen rack. The user places another specimen rack on the reader and inserts the newly removed specimen holder in a slot of the another specimen rack. The database is updated to reflect insertion of the specimen holder in a particular slot of the another rack.

Automatic tracking of a specimen holder moved from one specimen rack to another

A self-contained biological sample processing cartridge includes top and bottom portions that close together to form a sealed chamber therein. The chamber is configured to enable one of one or more biological sample staining procedures appropriate for a biological sample. The top portion includes a chamber top section and valve control elements. The bottom portion includes a chamber bottom section and fluidic valves. One of the fluid valves evacuates the contents of the chamber. One of the valve control elements couples to a respective fluidic valve to control fluid flow for the chamber. The cartridge includes a preloaded reagent component to supply the chamber with the reagent component appropriate for a particular biological sample staining procedure. A user desiring to conduct a particular biological sample staining procedure may select a particular cartridge that is preloaded with the preloaded reagent fluidic valves component appropriate for the particular biological sample staining procedure.

Self-contained sample processing cartridge with preloaded reagent

A specimen holder includes an RFID tag that exhibits an RFID unique identifier. The specimen holder also includes a barcode that exhibits a barcode unique identifier. The user may place a specimen holder in a particular rack slot of a multiple slot specimen rack that is situated on a specimen reader. The specimen reader may receive this specimen holder at accession time. The specimen reader reads both the RFID tag and the barcode of the newly inserted specimen holder. The specimen reader may correlate the RFID unique identifier and barcode unique identifier with one another and store the RFID unique identifier and barcode unique identifier associated with one another in a database. The database may also associate the RFID unique identifier and barcode unique identifier of the newly inserted specimen holder with a rack slot unique identifier that the database also stores.

Method of specimen tracking via barcode and RFID correlation at accession time

Described here are devices, systems, and kits for delivering substances to tissues. The devices generally include one or more chambers () and a reservoir () within each chamber. The reservoir may locally deliver a microdose amount of a substance to a target tissue. In some variations, a microdose amount is used in early human studies, e.g., before a phase I clinical trial, to evaluate the effect of the substance on a target tissue, or to obtain pharmacokinetic or metabolic data. In other variations, a microdose amount is used to locally treat a medical condition. In yet other variations, a microdose amount is used to locally deliver a contrast agent for a structural or functional imaging procedure. Methods for delivering and retrieving the devices from the target tissue are also described.

Device and method for drug evaluation and local treatment

Methods and compositions for treating a urothelial and/or a micropapillary carcinoma, such as a micropapillary urothelial carcinoma are disclosed.

Methods of treating urothelial carcinoma

Growing community of inventors

Lancaster, PA, United States of America

Jeffrey S Ross