Organetics, Ltd.

Biothermics, Inc.

IP Scientific, Inc.

Jeffrey P Sites

Philip R Glassel

Michael D Miller

Thomas A Roman

Dale J Ziebarth

Clark B Norgaard

Wei Chen

Method and apparatus to automatically monitor and control a perfusion hyperthermia treatment using a system including one or more programmed computers, and mechanical and sensor subsystems. The system includes a fluid path between a patient and an external fluid-treatment subsystem, wherein control of the external fluid-treatment subsystem includes feedback from sensors coupled to the patient. The resulting integrated system provides automated monitoring and control of the patient, the external fluid-treatment subsystem, and the treatment. In one embodiment, the fluid passing between the patient and the external fluid-treatment subsystem is blood. In one embodiment, an apparatus and method are provided for using a computerized system for a perfusion hyper/hypothermia treatment of a patient which obtains a body fluid having a temperature. A plurality of temperature signals representative of temperatures at each of a plurality of patient locations on or within the patient are coupled to the computer system. Measured temperatures are compared to a set of stored parameters in the computer system to generate a comparison value which controls a change in the temperature of the body fluid. The body fluid is then perfused into the patient to either warm, cool, or maintain the current temperature of the patient. In one such embodiment, the body fluid is blood withdrawn from the patient. In another such embodiment, the body fluid is saline.

Perfusion hyperthermia treatment system and method

Apparatus and a method for performing extracorporeal treatment of a patient's blood for various conditions. The apparatus includes means by which an extracorporeal blood circuit is defined. Such a blood flow circuit includes first means for cannulating a vein of a patient to define a blood egress point and second means for cannulating an artery of the patient to define a blood ingress point. A discontinuous conduit is provided to interconnect, in part, the first and second cannulating means. The apparatus also includes a module which includes a conduit portion. The module integrates a number of components into a single unit, and the conduit portion thereof is able to be interposed in the discontinuity in the discontinuous conduit to complete the blood flow circuit. The various components which are connected in the conduit portion include a pump, a device such as a heat exchanger to regulate the temperature of blood flowing through the conduit portion, and means for sensing the temperature, pressure, and flow rate of the blood passing through the conduit portion. In some applications, an oxygenator can also be included. A control console is provided to enable pressure and flow rate of the blood passing through the conduit portion to be controlled. Similarly, appropriate controls can be employed to regulate the temperature, and, when an oxygenator is included, a controller would, typically, be provided for the oxygenator also.

Apparatus and method for the extracorporeal treatment of the blood of a

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Plymouth, MN, United States of America

Jeffrey P Sites