University of Colorado

Jeffrey L Olson

Naresh Mandava

Michael Erlanger

Ramanath Bhandari

The present disclosure provides an adjustable endoscopic surgical device for illuminating a tissue surface with diffuse and oblique light. In some embodiments, light emanates from the sides of an optical fiber, which is optionally formed at least in part into a loop shape.

Adjustable loop fiber optic illumination device for surgery

An implantable device comprising a substrate capable of capturing an intraocular target molecule and to methods of use thereof. The substrate may be capable of capturing a target molecule present in the eye and/or from fluid of the eye (e.g., an intraocular target molecule). In some embodiments, the substrate has a relatively high affinity for a target molecule.

Intraocular filter device and methods of using same

The present disclosure provides an implantable device comprising a substrate capable of capturing an intraocular target molecule and to methods of use thereof.

Intraocular drug delivery and filter device and methods of using same

A device according to the present disclosure comprises an intraocular prosthetic. In some embodiments, the device comprises a lens portion and a plurality of arms that radiate outward from the lens portion. The lens portion can comprise a central ring used to hold an intraocular lens. Each arm can comprise a foot plate which allows the device to push out distally against a ciliary body. Among other things, an intraocular device according to the present disclosure can be useful in correction of aphakia, restoration of accommodation, and treatment of glaucoma.

Intraocular devices and methods for correction of aphakia, restoration of accommodation, and treatment of glaucoma

An injectable securement device includes one or more sutures and a bolster housed inside an elongate element, and may be part of a system that also includes one or more fastening elements and an elongate element. Injecting a suture tie/knot can be accomplished outside the eye without the need for performing the action of tying within the eye.

Injectable securement device and related delivery system and method of use

A glaucoma drainage device regulator (GDDR) is disclosed which comprises a membrane and a lumen to regulate the flow of aqueous in conjunction with different ocular (e.g., glaucoma) filtering procedures. In connection with aqueous shunting, the GDDR can be placed over the tip of a shunt tube in the anterior chamber, either at the time of initial surgery or also in devices which have been previously implanted. In connection with trabeculectomy, the GDDR can comprise a flange for seating the GDDR at the sclerostomy in trabeculectomy surgery.

Ocular filtration devices, systems and methods

An improved method for stimulating electrical activity in an eye is provided. Provided is a technique for implanting small, nanometer-sized photoactive devices into an eye to improve electrical activity within an eye or mitigate degradation of electrical response in damaged eyes.

Method for stimulating retinal response using photoactive devices

Exemplary embodiments comprise an implantable ophthalmic device comprising at least one shell encapsulating oxygenic bacteria and growth medium and designed to increase the oxygen partial pressure in an oxygen-deprived structure of, or space within, an eye. Exemplary embodiments may be used therapeutically to treat ischemic retinopathies in situ and thereby prevent damage, for example, retinal damage.

Growing community of inventors

Cherry Hills Village, CO, United States of America

Jeffrey L Olson