The Ohio State University

The Cleveland Clinic Foundation

Ohio State Innovation Foundation

Jeffrey J Chalmers

Ratnasingham Sooryakumar

Gregory B Vieira

Thomas Charles Henighan

Maciej Zborowski

Lee Robert Moore

James F Rathman

Weiwei Hu

Dhriti Sooryakumar

James R Rathman

A disposable kit for use in directing fluid through a biological cell separator device (). The kit generally includes a separator tube (), a buffer fluid container (), cell sample container (), separated cell container (), and flushing fluid container (), as well as various conduits () for connecting the containers () and separator tube () in fluid communication together. A cell separator system is provided including a separator tube (), magnet (), pump () and a motorized drive unit (). The motorized drive unit () is operatively connected to the magnet () to allow the magnet () to be moved a sufficient distance away from the separator tube () so as to allow cells adhered to the inside surface thereof to be flushed out of the tube ().

Biological cell separator and disposable kit

A magnetic platform is provided and includes a patterned array of discrete magnetic elements positioned on a substrate, a plurality of first electromagnets for creating a first magnetic field substantially in the plane of the substrate, an electromagnetic coil for creating a second magnetic field substantially perpendicular to the plane of the substrate, and a control device for controlling the application of the magnetic fields. Processes for manipulating, transporting, separating and sorting micro-or nano-scale particles and biomolecules are also described.

Magnetic platforms for biomolecule trappings, manipulations, and sorting

A magnetic platform is provided and includes a patterned array of discrete magnetic elements positioned on a substrate, a plurality of first electromagnets for creating a first magnetic field substantially in the plane of the substrate, an electromagnetic coil for creating a second magnetic field substantially perpendicular to the plane of the substrate, and a control device for controlling the application of the magnetic fields. Processes for manipulating, transporting, separating and sorting micro- or nano-scale particles and biomolecules are also described.

Compositions and methods for reducing gas-cell surface interface damage include a protective composition having at least sugar moiety where the sugar moiety provides a hydrophilic component to the protective composition.

Compositions for reducing cell adhesion to bubbles

Magnetic array platforms such as nano or micro-wire networks that produce trapping, manipulation, and transport of micro- or nano-scale particles such as non-biological entities such as magnetic particles and cells, viruses, DNA, proteins, and other biological entities having magnetic particles labeled or tethered thereto are provided. Methods of manipulating, transporting, and sorting micro- or nano-scale particles are described.

Growing community of inventors

Columbus, OH, United States of America

Jeffrey J Chalmers