Micromass UK Limited

Jeffrey Goshawk

Steven Derek Pringle

Michael McCullagh

Christopher Carver

Andrew Golding

David Eatough

Steve Smith

A method of screening a sample for at least one compound of interest is disclosed. The method comprises comparing the ion mobility and at least one further physicochemical property of the ions of a compound of interest to the same properties of candidate ions in the sample. The properties of the compound of interest are matched to those of a candidate ion in the sample then the sample may be determined to comprise the compound of interest.

Method of screening samples

A method of screening a sample for the presence of one or more known compounds of interest is disclosed. A fragmentation device is repeatedly switched between a fragmentation mode of operation and a non-fragmentation mode of operation. A determination is made whether a candidate parent ion of interest is present in a non-fragmentation data set and whether one or more corresponding fragment ions of interest are present in a fragmentation data set. A further determination is made to check if the candidate parent ion of interest and the one or more corresponding fragment ions of interest have substantially similar elution or retention times and/or ion mobility drift times.

Method of screening a sample for the presence of one or more known compounds of interest and a mass spectrometer performing this method

Growing community of inventors

Blackburn, United Kingdom

Jeffrey Goshawk