Other

Diversa Corporation

Jeffrey D Stein

Kevan M Shokat

Bonnie L Bassler

Michael G Surette

Stephan Schauder

Carol Dammel

Eric J Mathur

Martin Keller

Karl Rusterholz

George A Saer

The invention provides autoinducer-2 analogs that regulate the activity of autoinducer-2 and methods of using such analogs for regulating bacterial growth and pathogenesis.

Compounds and methods for regulating bacterial growth and pathogenesis

A method and device for collection and concentration of microbes via selectively attracting microbes to specific substrates chemically conjugated to a solid surface, such as a particle, are provided. Further, a method for selectively enriching for specific microorganisms using a device for collecting populations of microorganisms from an environmental sample comprising a solid support having a surface for attachment of an enrichment media is provided. The method for selectively enriching one or more populations of microorganisms from an in situ environment includes providing a device which has a container having a plurality of solid support particles in the container and a selective microbial enrichment media chemically attached thereto the particles. The container also has permeable openings for the microorganisms to provide entry of them therein so that the microbes will contact the enrichment media. The microorganisms are collected and concentrated in the device by placing it into the environment and the microorganisms are attracted to it and thereby migrate into the device through the permeable openings. The populations of microorganisms may be enriched in the device with a microbial attractant and growth inhibitor in the media and removed therefrom the device. The microorganisms enriched in the device include extremophiles. The solid support particles include glass, silica aerogel or a combination thereof. Glass beads may also be used as the solid support particles.

Microbial enrichment using a container having a plurality of solid support particles

Telephone set

Auxiliary telephone cradle

In a first preferred embodiment of the invention, a clip-on switching device is disclosed to prevent the placing of unauthorized outgoing calls from a (Touch Tone) telephone and/or to selectively switch an incoming call to an accessory (extension) telephone circuit. The switching device includes a housing which is particularly shaped to conform to the contour of the telephone cradle so as to be releasably connected therewithin. Positioned within the housing is a card having a control circuit thereon for selectively controlling the telephone circuitry. A unique spring-biased light emitting diode push-button switch is associated with the instant switching device, whereby to provide a visible signal, so as to indicate the operation of the telephone control circuit. In a second preferred embodiment of the invention, a telephone circuit hold device is provided which can be releasably connected to a (Touch Tone) telephone to permit the recipient of an incoming call to return his telephone handset to the telephone cradle whereby to temporarily place the existing call in a hold condition. The hold device includes an actuator assembly which is particularly structured for movement into physical contact with an associated circuit of the hold device, to selectively activate said circuit in order to place the telephone circuits in the hold condition.

Clip-on electronic switching and hold devices for telephones

A housing for containing accessory controls for an associated telephone mountable within the cradle of the telephone which conforms with the contour of the telephone and has positioned within the housing a card for selectively controlling the circuitry of the telephone.

Clip-on electric lock and switching device for telephone

Growing community of inventors

San Diego, CA, United States of America

Jeffrey D Stein