Anadys Pharmaceuticals, Inc.

Scriptgen Pharmaceuticals, Inc.

Jeffrey B Moore

John D Bradley

C Richard Wobbe

Craig M Thompson

Judith M Healy

Caroline E Donnelly

David A Bailey

The invention provides novel yeast cells comprising genes whose expression can be modulated by growth in the presence or absence of metal ions, methods for making such yeast cells, and methods of using such yeast cells for determining the requirement for expression of particular genes for the growth or viability of the yeast cells. The invention also provides methods of using such yeast cells in the isolation, screening and analysis of candidate antifungal compounds.

Regulated gene expression in yeast and method of use

The invention provides novel yeast cells comprising genes whose expression can be modulated by growth in the presence or absence of metal ions, methods for making such yeast cells, and methods of using such yeast cells for determining the requirement for expression of particular genes for the growth or viability of the yeast cells.

Regulated gene expression in yeast

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Brookline, MA, United States of America

Jeffrey B Moore