Thermo Fisher Scientific Oy

Qt Holdings Corp

Jeffrey A Zonderman

Vesa Nuotio

John Edward Brann, Iii

Joseph L Herman

Terry N Olney

Robert Dewitte

Jukka Saukkonen

Juhani Siidorov

Raimo Salminen

Joseph M Senteno

Jarmo Vehkomaki

Bill Ostman

Sean H Kevlahan

Brian D Plouffe

John Edward Iii Brann

A method of multiplexing the operation of a sample preparation and analysis system is disclosed. The system includes a sample preparation system capable of preparing a first sample in accordance with a first assay that is selected from a database containing a plurality of unique assays and preparing a second sample in accordance with a second, different assay. The method includes separately transporting the first and second prepared samples to an analysis station having first and second separation channels and an analyzer comprising a mass spectrometer. The method further includes simultaneously analyzing the first prepared sample with the analyzer in accordance with the first selected assay and separating the second prepared sample with the second separation channel in accordance with the second selected assay.

Automated system for sample preparation and analysis

The invention features shaped articles containing a structure and a hydrogel coating thereon, the hydrogel coating containing alginic acid conjugated to a polyalkylene oxide and a binding moiety. The hydrogel coating on the structure is sized and shaped to fit in a well in a microtiter plate and the coating does not cover the entire exterior of the surface. The invention further features methods of capturing targets using shaped articles and methods of preparing shaped articles.

Shaped articles including hydrogels and methods of manufacture and use thereof

A sample preparation and analysis system. The system includes a sample preparation system and a sample analysis system. The sample preparation system prepares samples in accordance with an assay that is selected from a database containing a plurality of unique assays. The sample analysis system includes an analyzer that is dynamically reconfigurable based on the selected assay so as to analyze the prepared sample in accordance with that selected assay. A data communication link communicates data from the sample preparation system to the sample analysis system to reconfigure the analyzer in accordance with the selected assay.

A sample preparation and analysis system. The systemincludes a sample preparation systemand a sample analysis system. The sample preparation systemprepares samples in accordance with an assay that is selected from a database containing a plurality of unique assays. The sample analysis systemincludes an analyzerthat is dynamically reconfigurable based on the selected assay so as to analyze the prepared sample in accordance with that selected assay. A data communication linkcommunicates data from the sample preparation systemto the sample analysis systemto reconfigure the analyzerin accordance with the selected assay.

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Westwood, MA, United States of America

Jeffrey A Zonderman